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isomerdesign

Perphenazine

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Perphenazine

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Perphenazine

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Perphenazine

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Data

InChI: InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2

Synonyms: 1-(2-Hydroxyethyl)-4-(3-(2-chloro-10-phenothiazinyl)propyl)piperazine,MFCD00056798,.gamma.-(4-(.beta.-Hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine,Spectrum2_001602, Emesinal,MLS001146929,AKOS000664046, P 6402,NCGC00015826-03,A831863,HMS2093M15,Perphenazine, European Pharmacopoeia (EP) Reference Standard, 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol, 2-Chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine,MLS002548897,Chlorpiprazine,2-Chloro-10-3-[1-(2-hydroxyethyl)-4-piperazinyl]propyl phenothiazine,Perphenazine, United States Pharmacopeia (USP) Reference Standard,D82041,1',1-(2-Idrossietil)-4,3-(2-cloro-10-fenotiazil)propilpiperazina, Perphenan,SPBio_002109,Etaperazin,component of Triavil (Salt/Mix),NINDS_000880,CCG-39060,DSSTox_GSID_23441,PERPHENAZINE [USP-RS],NCGC00015826-02,perphenazine, Tranquisan,SPECTRUM1503934,Emesinal,Decentan,Spectrum4_000843,Z1530532754, 4-(3-(2-Chlorophenothiazin-10-yl)propyl)-1-piperazineethanol,HMS3370O14,Lopac-P-6402,PERPHENAZINE [MI],Q423520,2-(4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol #,DB00850, Perfenazina [INN-Spanish],s4731, 4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol,EU-0072164,1-Piperazineethanol, trihydrochloride, Perphenazine (JP15/USP/INN),Perfenil,2-(4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol,BRD-K10995081-001-05-5,FTA7XXY4EZ,gamma-(4-(beta-Hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine,ETRAFON-A COMPONENT PERPHENAZINE,Spectrum5_001493,Lopac0_000930,KBio2_007226,CS-5137,GTPL209,Perphenazine maleate [JAN],1-Piperazineethanol, 4-[3-(2-chlorophenothiazin-10-yl)propyl]-,FLUPHENAZINE DIHYDROCHLORIDE IMPURITY E [EP IMPURITY], Perfenazina, Trilifan,HMS2095I12,Oprea1_603835,Chlorperphenazine, Perphenazine [Trilafon],NCGC00024092-03,2-[4-[3-(2-Chlorophenothiazin-10-yl)propyl]-piperazin-1-yl]ethanol,BRD-K10995081-001-15-4,1',1-(2-Idrossietil)-4,3-(2-cloro-10-fenotiazil)propilpiperazina [Italian], Triavil (TN),BPBio1_000188,2-(4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethan-1-ol,AI3-50151, 2-Chloro-10-(3-(1-(2-hydroxyethyl)-4-piperazinyl)propyl)phenothiazine, 2-Chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine,Prestwick2_000125,SR-01000000137-8,UNII-FTA7XXY4EZ,FT-0603244,DSSTox_RID_77031,L000919, 1',1-(2-Idrossietil)-4,3-(2-cloro-10-fenotiazil)propilpiperazina,D00503,NSC-150866,Fentazin,HMS3259C09,SDCCGSBI-0050904.P004,SBI-0050904.P003, Triphenot,PERPHENAZINE [WHO-DD],2-Chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine,PERPHENAZINE COMPONENT OF ETRAFON-A, Ethaperazine,Perphenazinum,Prestwick1_000125, Etaperazin,AB00052390_17,1-Piperazineethanol, 4-(3-(2-chlorophenothiazin-10-yl)propyl)-,PERPHENAZINE [JAN],1-(2-Hydroxyethyl)-4-[3-(2-chloro-10-phenothiazinyl)propyl]piperazine, Perphenazine maleate,Trilafon,DTXSID1023441, Decentan, Siquil (TN),NCGC00015826-07,Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)-, Fentazin, Gamma-(4-(beta-Hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine,Trifaron,4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol, 2-Chloro-10-3-(1-(2-hydroxyethyl)-4-piperazinyl)propyl phenothiazine, Chlorpiprazine,MRF-0000509,PERPHENAZINE [ORANGE BOOK], 4-[3-(2-Chlorophenothiazin-10-yl)propyl]-1-piperazineethanol,MLS000069637,2-Chloro-10-3-(1-(2-hydroxyethyl)-4-piperazinyl)propyl phenothiazine,BIDD:GT0150,SR-01000000137,PERPHENAZINE [HSDB],NSC150866,SMR000058180,NSC-758649,NSC 150866,Spectrum_001610,HMS502L22,KBio2_002090,NCGC00015826-10, Perphenazin,KBioSS_002090,58-39-9,Spectrum3_000758,Perphenazine 1.0 mg/ml in Methanol, 1',1-(2-Idrossietil)-4,3-(2-cloro-10-fenotiazil)propilpiperazina [Italian],Trilifan,2-{4-[3-(2-Chloro-phenothiazin-10-yl)-propyl]-piperazin-1-yl}-ethanol,HSDB 3379,.gamma.-[4-(.beta.-Hydroxyethyl)piperazin-1-yl]propyl-2-chlorophenothiazine,NCGC00015826-09,DSSTox_CID_3441,SR-01000000137-4,2-Chloro-10-(3-(1-(2-hydroxyethyl)-4-piperazinyl)propyl)phenothiazine, Sch 3940,NCGC00261615-01,PERPHENAZINE [INN], SCH-3940,Sch 3940,KBio2_004658,PERPHENAZINE [VANDF],C07427,HMS1568I12, Apo-Perphenazine,KBio1_000880,PERPHENAZINE [MART.],Perphenan, Perphenazinum [INN-Latin],Perphenazine,Perfenazina,CHEMBL567, 2-(4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol,Etaperazine,2-Chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine,HMS2232D21, Trilafon,BSPBio_000170,P1970,Ethaperazine,Tox21_110233, Etaperazine,HMS3262J22,NCGC00024092-05,NCGC00015826-08, 2-[4-[3-(2-Chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol,Tox21_500930,AB00052390,NCGC00015826-13,1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)-,Pharmakon1600-01503934,Prestwick3_000125,Prestwick_536,2-(4-(3-(2-Chloro-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethanol,Perfenazine, Trifaron,Perphenazin,4-[3-(2-Chlorophenothiazin-10-yl)propyl]-1-piperazineethanol,P 6402,Thilatazin,LP00930,NCGC00015826-01,Opera_ID_1161, 1-(2-Hydroxyethyl)-4-[3-(2-chloro-10-phenothiazinyl)propyl]piperazine,REGID_for_CID_4748,Etrafon (Salt/Mix),Prestwick0_000125, Perphenazine [INN:BAN:JAN],EN300-120640,1-Piperazineethanol, 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-,5,7-EICOSADIYNOICACID,ZINC19228902,SPBio_001603,PERPHENAZINE [USP MONOGRAPH],NCGC00015826-20,2-[4-[3-(2-Chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol,SR-01000000137-5,STK019818,2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethan-1-ol, Thilatazin,HMS3712I12,PERPHENAZINE [EP MONOGRAPH],Perphenazine, British Pharmacopoeia (BP) Reference Standard,W-105390,PZC,Tox21_110233_1, F-mon,EINECS 200-381-5,DivK1c_000880,WLN: T C666 BN ISJ EG B3- AT6N DNTJ D2Q,CAS-58-39-9,AC-12196,SCHEMBL42125,Triphenot,NCGC00015826-06,HMS3885H20,NCGC00015826-05, 2-Chloro-10-3-[1-(2-hydroxyethyl)-4-piperazinyl]propyl phenothiazine,IDI1_000880, Gamma-[4-(beta-Hydroxyethyl)piperazin-1-yl]propyl-2-chlorophenothiazine,Perfenazina [INN-Spanish],2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol,KBioGR_001445,NSC758649,HMS1922M14,NCGC00024092-06, 1-Piperazineethanol, 4-[3-(2-chlorophenothiazin-10-yl)propyl]-, trihydrochloride,BSPBio_002376,BDBM50130273,Perphenazine (JP17/USP/INN),Perphenazine [USP:INN:BAN:JAN],KBio3_001596,DB-053200,F-mon,NCGC00024092-04,EU-0100930,4-(3-(2-Chlorophenothiazin-10-yl)propyl)-1-piperazineethanol,Piperazineethanol, 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-,NC00472,NCGC00015826-04,Perphenazinum [INN-Latin],SCH-3940, 1-(2-Hydroxyethyl)-4-(3-(2-chloro-10-phenothiazinyl)propyl)piperazine,SR-01000000137-2,CHEBI:8028, Perfenazine,KS-5105,Tranquisan,HY-A0077, Perphenazinum,Perfenazina [Italian],Perphenazine for system suitability, European Pharmacopoeia (EP) Reference Standard, Perfenazina [Italian]

Estimated data

Solubility: -3.094 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: Yes (prediction using frontiersin.org)

Addictivity Prediction: 27.1% (prediction based on www.mdpi.com)

Similarities

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.