WHC is still in active development. Read this to understand our approach.
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isomerdesign

Imipramine

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pubchem

Imipramine

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drugmap

Imipramine

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Imipramine

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Data

InChI: InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3

Synonyms: Dpid,NCGC00015563-25,Berkomine,AB00053486-15,N-(.gamma.-Dimethylaminopropyl)iminodibenzyl,Melipramine,KBio3_001392,3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine,KBioSS_001395,Tofranil (Salt/Mix),Lopac0_000702,Q58396,3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, Norfranil,5H-Dibenz[b, 10,11-dihydro-N,N-dimethyl-,Tofranil (hydrochloride),Prestwick3_000072,Impramine,BRD-K38436528-003-15-4,SY246340,BSPBio_002172,Irmin, SK-Pramine,N,N-Dimethyl-10,11-dihydro-5H-dibenzo[b,f]azepine-5-propanamine-2,8-D2,DSSTox_CID_23881,Dyna-zina,Clomipramine EP Impurity B; 10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine,Dimipressin,Imipraminum [INN-Latin],3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine #,5H-Dibenz(b, 5-(3-(dimethylamino)propyl)-10,11-dihydro-, Imipramina [Italian],ZINC20245, Surplix (TN),KBio2_003963, 5,6-Dihydro-N-(3-(dimethylamino)propyl)-11H-dibenz(b,e)azepine,N-(3-Dimethylaminopropyl)-o-iminodibenzyl,GTPL357, Dimipressin,CCRIS 9173,Imavate (Salt/Mix),N-(gamma-Dimethylaminopropyl)iminodibenzyl,5H-Dibenz[b, 5-[3-(dimethylamino)propyl]-10,11-dihydro-,Antideprin,NCGC00015563-04,Imizin (Salt/Mix), 2,2'-(3-Dimethylaminopropylimino)dibenzyl,Prestwick1_000072,TRIMIPRAMINE MALEATE IMPURITY, IMIPRAMINE- [USP IMPURITY], 5H-Dibenz(b,f)azepine,5-[3-(dimethylamino)propyl]-10,11-dihydro-mixed with ethyl alcohol,WLN: T C676 BN&T&J B3N1&1, N-(gamma.-Dimethylaminopropyl)iminodibenzyl, Prazepine,Spectrum4_000016,NCGC00015563-07,3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine;3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine, Timolet, 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine,3-(10,11-Dihydro-5H-dibenz[b,f]azepin-5-yl)-N,N-dimethylpropylamine,IMIPRAMINE [VANDF],Surplix, Imipraminum [INN-Latin],Spectrum_000915, Tofranil(TN),BRN 0256892,Clomipramine HCl EP Impurity B, Imipramina,5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz[b,f]azepine;10,11-Dehydroimipramine;Depramine,SBI-0050680.P004,Janimine (hydrochloride), Pramine,NCGC00015563-06,Psychoforin (Salt/Mix),HSDB 3100, Intalpram,CS-0013621,Melipramin,NSC 169866,Spectrum5_000864, Imipramil (TN),DTXSID1043881,Nelipramin, Tofranil,5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)propyl)-,NINDS_000559,C07049,1-(3-Dimethylaminopropyl)-4,5-dihydro-2,3,6,7-dibenzazepine, 2,2'-(3-Dimethylaminopropylimino)bibenzyl, Dyna-zina, 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine,EINECS 200-042-1,CLOMIPRAMINE HYDROCHLORIDE IMPURITY B [EP IMPURITY],5,e)azepine,STL416211,Imavate,3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-propan-1-amine, Janimine (hydrochloride),IMIPRAMINE [WHO-DD],Sermonil,Imipraminum, 5,6-Dihydro-N-[3-(dimethylamino)propyl]-11H-dibenz[b,e]azepine, 10,11-Dihydro-5-(3-(dimethylamino)propyl)-5H-dibenz[b,f]azepine, Janimine, Iramil,IXX,L000739, Tofranil, base,DSSTox_GSID_43881, Imipramina [INN-Spanish],Imidobenzyle,2,2'-(3-Dimethylaminopropylimino)bibenzyl, Janimine (TN), Nelipramin, Tofranil (free base),Trimipramine maleate impurity, imipramine-,Tox21_110174,Imiprin,KBio1_000559, 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenzo(b,f)azepine, Censtin,Prestwick2_000072, Imidobenzyle,Spectrum2_000990,Tox21_110174_1,Declomipramine,SPBio_001059,NCGC00015563-08, Declomipramine,IMIPRAMINE [MI],SDCCGSBI-0050680.P005, 1-(3-Dimethylaminopropyl)-4,5-dihydro-2,3,6,7-dibenzazepine,Imidol,Spectrum3_000466,BSPBio_000283, Dynaprin, Imiprin, Melipramin (TN),Eupramin (Salt/Mix), Impramine,NCGC00015563-02, Melipramin, Imipramine [INN:BAN],5-(3-(Dimethylamino)propyl)-10,f)azepine, Imipraminum,IMIPRAMINE [MART.],Imipramina,5-(3-Dimethylaminopropyl)-10,f)azepine,5H-Dibenz(b, 10,11-dihydro-5-(3-(dimethylamino)propyl)-, Imipramine (INN), Melipramine,3-(10,11-dihydro-5h-dibenz[b,f]azepin-5-yl)propyldimethylamine,5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, Imizinum,SCHEMBL34282,Imizin, Antideprin (TN),NCGC00024253-04,Imipramin, Deprinol (TN),Psychoforin,Dynaprin,5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)-10,11-dihydro-,Intalpram, Depsonil (TN),5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)propyl]-10,11-dihydro-,Imipramina [INN-Spanish],D08070,Censtin,2241983-10-6,1-(3-Dimethylaminopropyl)-4,3,6,7-dibenzazepine,Prestwick0_000072,5,6-Dihydro-N-(3-(dimethylamino)propyl)-11H-dibenz(b,e)azepine,Lopac-I-7379,FT-0670319,SK-Pramine (Salt/Mix),W-109253, Imizin,G-22355 (Salt/Mix),2,2'-(3-Dimethylaminopropylimino)dibenzyl,Cristalia,Tofranil,DB00458, Deprimin (TN),AB00053486_16,5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenzo(b,f)azepine, Censtim,Tofranil (free base),DSSTox_RID_80080,TRIMIPRAMINE MALEATE IMPURITY D [EP IMPURITY], Irmin,SPBio_002204,KBioGR_000391,UNII-OGG85SX4E4,Eupramin, Dynaprin (TN),NCGC00015563-13,IMIPRAMINE [HSDB],AB00053486_17,HY-B1490A,3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine,KBio2_001395,CCG-36485,IMIPRAMINE [INN], Tofraniln A,50-49-7,BRD-K38436528-003-05-5, Tofranil (hydrochloride),Surplix (Salt/Mix),5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-,10,11-Dihydro-5-(3-(dimethylamino)propyl)-5H-dibenz[b,f]azepine,NSC169866, Promiben,AKOS016010320,imipramine,EN300-708790, Eupramin,BPBio1_000313,FT-0697093, Dpid,AB00053486, Berkomine, Eupramin (TN),Imizinum,Tofranil base,Imipramina [Italian],CAS-113-52-0,NCGC00015563-11,Imipramine, N-(gamma-Dimethylaminopropyl)iminodibenzyl,Imizine (Salt/Mix),MRF-0000592, Norchlorimipramine,NCGC00024253-03,(3-{2-azatricyclo[9.4.0.0,3,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)dimethylamine,Tofranil (TN),Imipramine (INN), 10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine,NCGC00015563-10,Iramil, Imavate,NCGC00015563-09,DivK1c_000559, 5-(3-(Dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine,10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine,5-(3-(Dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine, G-22355,SK-Pramine,5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine,BDBM50010859,MFCD31699979,NCGC00015563-03,Imipramine [INN:BAN],NCGC00015563-01, N-(3-Dimethylaminopropyl)-o-iminodibenzyl,3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine,NSC-169866,BIDD:GT0116,Janimine,Tofranil, base,CHEBI:47499,ORG-2463, Surplix,5H-Dibenz(b,5-[3-(dimethylamino)propyl]-10,11-dihydro-mixed with ethyl alcohol,IDI1_000559,NCGC00015563-05,Oprea1_200908,Censtim,OGG85SX4E4,Timolet,KBio2_006531, Imipramin,Imizinum (Salt/Mix), 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-(9CI),(3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)dimethylamine,CAS-50-49-7,Promiben, Irmin (TN),5,e]azepine,HMS2089G08,CHEMBL11

Estimated data

Solubility: -3.578 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: Yes (prediction using frontiersin.org)

Addictivity Prediction: 27.3% (prediction based on www.mdpi.com)

Similarities

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.