WHC is still in active development. Read this to understand our approach.
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promethazine

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Promethazine

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Promethazine

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Promethazine

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Promethazine

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Promethazine

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Promethazine

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Data

InChI: InChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3

Synonyms: Pyrethiazine,C07404, Farganesse (TN),promethazine,73745-50-3, Prothazine,Histargan,10-(2-Dimethylaminopropyl)phenothiazine, Pyrethiazine, Fenetazine,AB00053535-12, Diprozin,NCGC00015817-08, Fargan,SR-01000002993-10,10H-Phenothiazine-10-ethanamine,N,.alpha.-trimethyl-,EX-A891,4-27-00-01253 (Beilstein Handbook Reference),Dimethylamino-isopropyl-phenthiazin,Hiberna,DB01069, Promethazinum,Romergan,HMS2089E08, SKF 1498, Prorex,N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine hydrochloride, Promethiazine,SPBio_002895,Iergigan, Prothiazine (TN),CHEMBL643, Promethegan (TN),PROMETHAZINE [MI],NSC30321,NCGC00015817-10, Phenerzine,F17386,KBio2_001348, Prometazin,(.+/-.)-Promethazine,KBioSS_001348,Pyrethia,PROMETHAZINE [WHO-DD], Proazaimine,Pelpica,SKF 1498,KBio3_001997,(+/-)-10-(2-(DIMETHYLAMINO)PROPYL)PHENOTHIAZINE,NCGC00015817-12, Atosil (TN), A-91033,Fenazil, Iergigan, Prometazina,KBio2_003916,Oprea1_758749,AKOS015962127,IDI1_000005,Pro-50,Phenothiazine, 10-(2-dimethylaminopropyl)-,Provigan, Fargan (TN),NSC 30321, Lergigan (TN),Dimapp,60-87-7 (free base),KBioGR_001697,Phenoject-50,(+/-)-promethazine, Rumergan, Promergan,SR-01000002993,Spectrum5_000977,KBio1_000005, Pipolphene,DivK1c_000005, PromethazineHcl,PROMETHAZINE [VANDF],N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine, Camergan,Prestwick0_000888, Promethazin,FT-0700342,BSPBio_000676,Spectrum4_001149,WLN: T C666 BN ISJ B1Y1&N1&1,Avomine,Phensedyl, WY 509,Lopac0_000899, Proazamine,CAS-60-87-7,SCHEMBL4700, Metaryl,Metaryl,Pipolphene,N-(2'-Dimethylamino-2'-methyl)ethylphenothiazine, Lercigan, Dimapp, Isophenergan,Dimethylamino-isopropyl-phenthiazin [German],Spectrum3_001019,GTPL7282,Prometazin, Phargan, Dimethylamino-isopropyl-phenthiazin, Prothazin,NSC-30321, Lergigan, Pyrethia,10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, radical ion(1+),N,N,.ALPHA.-TRIMETHYL-10H-PHENOTHIAZINE-10-ETHANAMINE,Prorex,WY 509, Fenazil,10-[2-(Dimethylamino)propyl]phenothiazine, Avomine,Tox21_110227_1,Prothazin,BPBio1_000744,NCGC00089735-03,AB00053535_13,Procit,3389 R.p., Hiberna,Prestwick1_000888,Proazamin,NCGC00015817-04,Fenetazine, Lilly 1516,MFCD00066294,Vallergine, Diprazine,Lergigan,Promethiazine,Valergine,Antiallersin, Promezathine,Diprozin,CHEBI:8461,10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-,Promethazine [INN:BAN], Promethacon,NCGC00015817-09, Promethazine [INN:BAN],NCGC00015817-17,FF28EJQ494, Provigan,Promergan,DSSTox_CID_3518,Fenetazina, RP 3277,Pipolphen (Salt/Mix), Phenargan,Lilly 1516,Promazinamide,NCI-C60673, Aprobit,Promethazinum [INN-Latin], Diprazin,Diprazine,Promethegan,Promethazine,NCGC00015817-06, Procit, Phensedyl,10-(2-(Dimethylamino)-2-methylethyl)phenothiazine, Promacot,Pyrethia (Salt/Mix), Promesan, Lilly 01516,38878-40-9,PromethazineHcl, Pro-50,Prometazina [INN-Spanish], Diphergan,Phargan,Remsed (Salt/Mix),D00494,S5196,dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine,NCGC00015817-05,J-690333,BRN 0088554,Sominex,10H-Phenothiazine-10-ethanamine, N,N,.alpha.-trimethyl-,Diphergan,Pilpophen,SDCCGSBI-0050874.P005,Tox21_110227, Prometazina [INN-Spanish],N,N-Dimethyl-1-(10H-phenothiazin-10-yl)-2-propanamine #, Phenoject-50,60-87-7, Isopromethazine,PHENOTHIAZINE, 10-(2-(DIMETHYLAMINO)PROPYL)-, Thiergan,NCGC00015817-03, Prometasin,CCRIS 7056,NCGC00015817-11, Promethazine (JAN/INN),10-(2-(Dimethylamino)propyl)phenothiazine,HSDB 3173,Thiergan,Phenargan,PWWVAXIEGOYWEE-UHFFFAOYSA-,Promezathine, Promethaine,Lercigan,Isophenergan,Promesan,Prometasin,Spectrum_000868,PROMETHAZINE [HSDB],DTXSID7023518, Romergan,N-Dimethylamino-2-methylethyl thiodiphenylamine,Promethacon,Pilothia,N,N-Dimethyl-1-(10H-phenothiazin-10-yl)-2-propanamine, Pelpica, Receptozine (TN),Prestwick3_000888, Remsed,CCG-109848,L000495, Romergan (TN),Q422970,Lilly 01516,Promethazine (JAN/INN),NCGC00015817-14,3277 RP,UNII-FF28EJQ494,RP-3277,PROMETHAZINE [JAN], Phenergan (TN), Zipan-25,(Dimethylamino-2-propyl-10-phenothiazine hydrochloride,SBI-0050874.P004,Spectrum2_000840,Prometazina,Promacot,EN300-708776, Valergine, Promazinamide, Promethazinum [INN-Latin],SPBio_000799,NCGC00015817-24,NINDS_000005,N,N,alpha-Trimethyl-10H-phenothiazine-10-ethanamine,Prometazine,A-91033, Promethegan,Protazine,BSPBio_002777,NCGC00089735-02,10-(2-DIMETHYLAMINO-2-METHYLETHYL)PHENOTHIAZINE,PROMETHAZINE [MART.],PROMETHAZINE [INN],Phenergan base,Fargan, Histargan, Dimethylamino-isopropyl-phenthiazin [German], Pilothia,Proazaimine,Promethazinum, Pilpophen, Avomine (TN), Prometazine,N,N-DIMETHYL-1-PHENOTHIAZIN-10-YL-PROPAN-2-AMINE,N,N-Dimethyl-1-phenothiazin-10-yl-propan-2-amine,Phenothiazine, 10-[2-(dimethylamino)propyl]-,Tanidil,Prothazine, Genphen, Protazine,KBio2_006484, Tanidil, Vallergine,AB00053535,Prestwick2_000888,Prometh,NCI60_001878,DSSTox_GSID_23518, Prometh,EINECS 200-489-2,4182 R.p.,10H-Phenothiazine-10-ethanamine,N,N,b-trimethyl-,AC-15939,Camergan,BDBM50017696,N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine, Fenetazina,RP 3277,Promethazin,Proazamine,Phenerzine,10H-PHENOTHIAZINE-10-ETHANAMINE, N,N,.ALPHA.-TRIMETHYL-, (+/-)-,(2-Dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine,DSSTox_RID_77061


Estimated data

Solubility: -3.707 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: Yes (prediction using frontiersin.org)

Addictivity Prediction: 22.4% (prediction based on www.mdpi.com)

Similarities

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.