WHC is still in active development. Read this to understand our approach.
depiction of BNRNXUUZRGQAQC-UHFFFAOYSA-N.svg
isomerdesign

Sildenafil

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Sildenafil

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Rhucin

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Rhucin

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Sildenafil

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Data

InChI: InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)

Synonyms: 5-[2-ethoxy-5-(4-methylpiperazine-1-sulfonyl)phenyl]-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin-7-one,SILDENAFIL [MI],SILDENAFIL [EMA EPAR],STL483720, VIAGRA,5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin-7-one,EN300-117245,DivK1c_006894,Patrex,HMS1684K08,SR-01000504734,Spectrum4_000586,SCHEMBL5795456, BNRNXUUZRGQAQC-UHFFFAOYSA-N, 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine,Spectrum_001555, 5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one,HMS3740G19,Sildenafil- Bio-X,HSDB 7305,SILDENAFIL; VIAGRA,AB00052444_05,C07259,D08514, UNII-3M7OB98Y7H,ZINC19796168,BRD-K79759585-048-01-4,AB00052444_04,AKOS037623334,SBI-0051920.P002,5-[2-ethoxy-5-(4-methylpiperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo(4,3-d]pyrimidin-7-one,1-((3-(6,7-DIHYDRO-1-METHYL-7-OXO-3-PROPYL-1H-PYRAZOLO(4,3-D)PYRIMIDIN-5-YL)-4-ETHOXYPHENYL)SULFONYL)-4-METHYLPIPERAZINE,3-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonyl-phenyl]-7-methyl-9-propyl-2,4,7,8-tetrazabicyclo[4.3.0]nona-2,4,8,10-tetraen-5-ol,KBioGR_001052,Piperazine, 1-((3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methyl-,Q191521,SR-01000504734-1,KBio2_007171,STL565123,BRD-K79759585-001-02-1,5-[2-Ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl]-1-methyl-3-n-propyl-1.6-dihydro-7H-pyrazolo[4,3-d]Pyrimidin-7-one,Sildenafil,MFCD00867528,KBioSS_002035,Sildenafil [INN:BAN],1xos,SILDENAFIL [INN],BDBM14390,5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, HSDB 7305,KBio2_004603,VIAGRA,Aphrodil (TN),5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one,Sildenafil#, Sildenafil,MLS001240224,1udt,HMS3372N07,HMS2093O17,BS164403,SMR000752512,CHEBI:9139, C22H30N6O4S,BIDD:GT0352, Sildenafil [INN:BAN],Spectrum3_001892,AC-938,5-{2-(ethyloxy)-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one,HMS2233L22,CCG-39076, UK-92480, 3M7OB98Y7H,DTXSID6023579,KBio3_002927,sildenafil,UK 92480-10,5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one,NCGC00095099-01,AB00052444-03,UNII-3M7OB98Y7H,5-[2-Ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one,3M7OB98Y7H,AKOS008901403,KBio1_001838,755S832,Aphrodil,Sildenafil ratiopharm, 139755-83-2,Sildenafil 1.0 mg/ml in Methanol,NCGC00095099-03,SILDENAFIL [HSDB],5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE,Sildenafil (INN),Sildenafil teva,HMS1922B19,Z1522567175,5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propylpyrazolo[4,3-d]pyrimidin-7-ol,Spectrum2_001648,BCP05337,AS-48884,5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, UK-92,480-10,FT-0674582,Cambridge id 7030299,HY-15025,5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one,GTPL4743,Spectrum5_001508,5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one,UK-92480, CHEMBL192,CCG-21806,Sildenafil actavis,s4684,AB00052444-02,Sildenafil Impurity J,SR-05000001934,PIPERAZINE, 1-((3-(6,7-DIHYDRO-1-METHYL-7-OXO-3-PROPYL-1H-PYRAZOLO(4,3-D)PYRIMIDIN-5-YL)-4-ETHOXYPHENYL)SULFONYL)-4-METHYL-,MLS006011565,BRD-K50128260-001-01-6,SILDENAFIL [VANDF],CS-1577,Viagra,2h42,SR-05000001934-1,Sildenafil solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material,CHEMBL192,HIP-0908,1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine,HMS2089M12,DB00203,5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7-ol,NCGC00370976-03,Vizarsin,NCGC00095099-02,SB17345,SMR004703325,BSPBio_003424,FD12062,KBio2_002035,STL483201,AKOS025397193,5-{2-ethoxy-5-[(4-methylpiperazine-1-)sulfonyl]phenyl}-1-methyl-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one, CHEBI:9139,SR-05000001934-2,SILDENAFIL [WHO-DD],MLS001304737,ACT02662,NCGC00159496-02, UK 92480-10,SPBio_001775,NCGC00095099-04,AMY39053,139755-83-2,SCHEMBL8100377,SCHEMBL1895,HIP0908,SPECTRUM1504099,SpecPlus_000798,J-007309,HMS3715P17,5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonyl-phenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one,5-[2-ethoxy-5-(4-methylpiperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

Estimated data

Solubility: -4.093 (log(S) in mol/L prediction using SolTranNet)

Addictivity Prediction: 17.1% (prediction based on www.mdpi.com)

Similarities

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.