Clozapine
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Clozapine
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Clozapine
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Clozapine
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Data
InChI: InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
Synonymes: Clozapine,NCGC00022902-11, Clozapin,J60AR2IKIC,Opera_ID_482,HMS3266A10,LEX-123,NCGC00022902-13,Fazaclo ODT,Versacloz,LX 100-129,CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE,Lopac-C-6305,NCGC00022902-05,CAS-5786-21-0,Prestwick_693,W-801,HMS3371H05,UNII-J60AR2IKIC,Bio2_000790,NCGC00015254-31, 3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepine, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo (b,e)(1,4)diazepine,NCGC00015254-11,KBioSS_000310,NCGC00015254-04,HSDB 6478, Clozapinum [INN-Latin],Fazaclo, Klozapol (TN),CLOZAPINE [WHO-DD],Bio1_001414,8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine), W-801,Tox21_500276,Clozapine for peak identification,CLOZARIL,ZINC19796155,Clozapinum [INN-Latin],MFCD00153785,SCHEMBL8397,CHEBI:92657,KBio2_000310,NCGC00022902-12,CHEBI:3766,8-Chloro-11-(4-methylpiperazino)-5H-dibenzo[b,e][1,4]diazepine,KBioSS_000599,CLOZAPINE (TEVA) [VANDF],HF-1854,Clozapine - Bio-X,NCGC00022902-07,3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepine,8-Chloro-11-(4-methylpiperazine-1-yl)-5H-dibenzo[b,e]-[1,4]diazepine,CLOZAPINE (MYLAN) [VANDF], 8-Chloro-11-(4-methyl)-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine,CLOZAPINE (VERSACLOZ) [VANDF],NCGC00015254-03,NCGC00015254-08,CLOZAPINE (UDL) [VANDF], Clopine (TN),Azaleptine,Spectrum4_000898,DSSTox_CID_2855,KS-1166,D-107,NCGC00260961-01, Leponex (TN), HF1854,NCGC00015254-06,AKOS026749900,REGID_for_CID_2818,6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0,3,8]pentadeca-1,3(8),4,6,10,12,14-heptaene,HF 1854,Clozapine (caraco),Clozapinum,CLOZAPINE [INN],Clozapin,Clozapine, European Pharmacopoeia (EP) Reference Standard, Clozapina,8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine,KBioGR_000310,W-105432,SPECTRUM1500685, Fazaclo ODT,NCGC00015254-07,H10436,CLOZAPINE [USAN],8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine),KBio1_000343,NCGC00015254-02,CHEMBL42,Tox21_110113,HMS3260H14,Bio2_000310,NCGC00022902-08, Clozapine(tautomer), LX 100-129,SPBio_002340,NCGC00022902-10,1333667-72-3,SBI-0050264.P004, Froidir (TN),NCGC00015254-14,KBio2_003167,NCGC00015254-20,NCGC00015254-18,KBioGR_001336, HF-1854,Prestwick1_000350,BDBM50001884,SW220247-1, Clozapina [INN-Spanish],8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine,8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine ),MLS001077282, Fazaclo (TN),HMS3657E15,CLOZAPINE [USP-RS],HMS2089L13,Bio1_000436,MLS000028472,NCGC00015254-15,SR-01000000096-5,Tox21_110113_1,Clozapine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material,CLOZAPINE (CARACO) [VANDF],Iprox,Clozapine (Clozaril),HMS3678F09,Tocris-0444, Clozapine (JAN/USP/INN),CPD000058365, 8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine,DSSTox_GSID_22855,KBio2_000599,NSC757429,BRN 0764984,Clozapine for peak identification, European Pharmacopoeia (EP) Reference Standard,clozapine,NCGC00022902-06,KBio3_000620,Clozaril (TN), Clorazil,Clozapine (ivax),EU-0100276,EN300-52510, Zaponex (TN), Leponex,AB00052158-13,NSC 757429,BC164328, Lepotex,Clozapine (teva),Bio1_000925,HMS1989P12,SR-01000000096,KBio3_002979,3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine,CLOZAPINE (FAZACLO) [VANDF],Clozapine, British Pharmacopoeia (BP) Reference Standard,CLOZAPINE [JAN],Prestwick0_000350,Clorazil,8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]-diazepine,GTPL38, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]-diazepine,8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine),HMS3414F09,8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine,CLOZAPINE [EP MONOGRAPH],HMS3259J17,DB00363,EINECS 227-313-7,NCGC00015254-16,CLOZAPINE (IVAX) [VANDF],NSC-757429,Clozapine (udl),8-Chloro-11-(4-methyl)-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine,HMS2096E21,LP00276,Clozapine (mylan),AB00052158-14,Q221361,DivK1c_000343,Clozapine [USAN:USP:INN:BAN],SPBio_000798,CLOZAPINE RESOLUTION MIXTURE [USP-RS],BRD-K37289225-001-23-2,Clozapine (JAN/USP/INN),Clozapine, drug standard, 1.0 mg/mL in methanol,Clozapine, solid,Clozapine Resolution Mixture, United States Pharmacopeia (USP) Reference Standard,6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene,Z754926488,HMS2235E19,NCGC00015254-13,HMS3402P12,NCGC00015254-10, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine, LEX-123,6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,9,12,14-heptaene,DTXSID5022855,3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine,NCGC00015254-17,SR-01000000096-2,5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-,CLOZAPINE [MART.],Leponex, CLOZARIL,BRD-K37289225-001-09-1,HMS3742K03,SMR000058365,L013417,BCP25196,5786-21-0,CLOZAPINE [USP MONOGRAPH],CLOZAPINE [ORANGE BOOK],SR-01000000096-4,5H-Dibenzo(b,e)(1,4)diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-,Clozapine 1.0 mg/ml in Acetonitrile,NCGC00015254-05,Asaleptin, 8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine,HMS501B05,Clozapine (versacloz),NINDS_000343,AB00052158_15,CLOZAPINE [HSDB],Clozapine (fazaclo),L000195,C 6305,AKOS005064444,SR-01000000096-8,KBio2_005446, Denzapine (TN),HY-14539,CLOZAPINE (CLOZARIL) [VANDF],CLOZAPINE [VANDF],DSSTox_RID_76759,BDBM22869,DB-053121,C06924,NCGC00015254-12,8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine,Pharmakon1600-01500685, Clozaril (TN),CCG-39881, Clozapinum,HMS2092I16,NCGC00015254-01,3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester, Clozapine [USAN:INN:BAN],(E)-8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine,CCRIS 9171,SDCCGSBI-0050264.P005,8-Chloro-11-(4-methyl-1-piperazinyl)-10H-dibenzo[b,e][1,4]diazepine,D00283,s2459,Clozapina,Clozapina [INN-Spanish],786C210,Spectrum3_001828,Spectrum_000139,Clozapine solution, Fazaclo,Clozapine, United States Pharmacopeia (USP) Reference Standard,KBio2_002878,AB00052158_16,SCHEMBL33323,KBio2_005735,HMS1791P12,NC00667,Clozapine resolution mixture,HMS1921C16,NCGC00022902-02,HMS3713E21, C 6305, KS-1166,NCGC00015254-09,NCGC00188978-01,ZINC3872123, Iprox,CLOZAPINE [MI],Lepotex,KBio3_000619,NCGC00022902-04,HMS1569E21,NCGC00022902-09,DTXSID401020663,Spectrum2_000919,8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine,HMS1361P12,CS-0644
Estimated data
Solubility: -3.537 (log(S) in mol/L prediction using SolTranNet)
Blood Brain Barrier Permeability: Yes (prediction using frontiersin.org)
Addictivity Prediction: 37.9% (prediction based on www.mdpi.com)
