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lorazepam

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Lorazepam

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Data

InChI: InChI=1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)

Synonymes: HMS2052H07,Nervistopl,IDI1_000965, Novartis Brand of Lorazepam, Lorazepam Wyeth Brand, Donix, Bonatranquan,LORAZEPAM [WHO-DD], Duralozam,SCHEMBL26961,o-Chloroxazepam,Quait,DSSTox_RID_76932,Lorsilan,Emotion, Wyeth Brand of Lorazepam,7-Chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one,Lorazepam preservative free, Lorazepam-Efeka,Lorazepam, United States Pharmacopeia (USP) Reference Standard, Medix Brand of Lorazepam,DB00186,Lopam,Lorazepam Medical,HMS503A11, Medical Brand of Lorazepam,Stapam, Lorazep, Novopharm Brand of Lorazepam,Apo-Lorazepam, Lorivan,7-chloro-3-hydroxy-5-(2'-chloro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepine-2-one, Renaquil,LORAZEPAM [ORANGE BOOK], Bonton, (+/-)-Lorazepam,Securit, Lorazepam Medical Brand,Ativan (TN), Tolid,7-chloro-3-hydroxy-5-(2'-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepine-2-one,NINDS_000965, Medical, Lorazepam, O-Chlorooxazepam,Tavor,Lorazepam, European Pharmacopoeia (EP) Reference Standard,LORAZEPAM [INN], Lorazepam Llorens Brand, Aplacasse,EINECS 212-687-6,Lorsedal, Lorazon, Nervistop L, Securit, Lorazepam (Ativan), Tranqipam,Pro dorm, Ativan,LORAZEPAM7-Chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one,Lorazepam, British Pharmacopoeia (BP) Reference Standard, Wyeth, Orfidal,NC00420,Lorat, Baxter Brand of Lorazepam,846L491,Wy 4036, Lorazepam (JP15/USP/INN), Sedizepan,Lorazin,O26FZP769L,Sedizepan,Novhepar, Larpose,Lorazon,Idalprem, Lorazepamum, Alzapam, Lorazepam-ratiopharm, Ativan (TN), Lorazepam Riemser Brand, Equitam,Lorazepam 0.1 mg/ml in Acetonitrile,Norlormetazepam, Lorazepam Dolorgiet Brand, Lorazepam preservative free, Novo-Lorazem,Lorax, Vigiten,Merlit,7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-1,4-benzodiazepin-2(3H)-one, Lorazep von ct, 7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one,Wypax, 7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one,LOREEV XR,LORAZEPAM [MI], Apo Lorazepam,BCP13713,LORAZEPAM [EP IMPURITY],Sinestron,Lorazene, Idalprem, Pro dorm,CCG-101170, Temesta, WY4036,KBio1_000965, Emotion,Q408265, Lorenin,Vigiten,7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one,DSSTox_GSID_23225,DivK1c_000965, Lorazepam Medix Brand, Ct-Arzneimittel Brand of Lorazepam,Tox21_111669,NSC 289758,MLS001424236,BRN 0759084, Dolorgiet Brand of Lorazepam,Lorazepam 1.0 mg/ml in Acetonitrile, L1764_SIGMA,UNII-O26FZP769L, 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one, Loridem, Lorazepam Desitin Brand, Lorazepam ratiopharm,2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-, Riemser Brand of Lorazepam,(RS)-9-chloro-6-(2-chlorophenyl)-4-hydroxy-2,5-diazabicyclo[5.4.0]undeca-5,8,10,12-tetraen-3-one, Lorazepam Genericon, Novhepar,Loraz,(+/-)-7-CHLORO-5-(O-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-2H-1,4-BENZODIAZEPIN-2-ONE,Lorans,Anxiedin,Sidenar, Lorazepam Novartis Brand,Temesta, Lorazepam neuraxpharm Brand,Orfidal,2H-1, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-, Merlit,7-chloro-5-(2-chlorophenyl)-3-hydroxy-2,3-dihydro-1H-1,4-benzodiazepin-2-one,Lomesta,Silence, Lorazepamum [INN-Latin], Durazolam,Renaquil,LORAZEPAM [VANDF],Almazine,Sedatival,Lorazepamum [INN-Latin], Azurogen,Bonton, Ratiopharm Brand of Lorazepam, Norlormetazepam, Lorabenz,DEA No. 2885, Anxiedin,Nervistop L, Lomesta,Demethyllormetazepam,Lorazepan Chobet, Wy 4036, Nu-Pharm Brand of Lorazepam,Efasedan, Trapax, Nervistopl, Wy-4036, O-Chloroxazepam,Lorenin,7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one, Lozepam, Lorafen,7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one #,o-Chlorooxazepam,LORAZEPAM [MART.], Lorazepam Novopharm Brand, Sedatival,Upan,Max Pax,7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one,Larpose, Novolorazem,846-49-1,Lorazepam civ, Silence, Lorazepam Lannacher, Loraz, Ct Arzneimittel Brand of Lorazepam, Lorzem,2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-, (+-)-, Anxira,CAS-846-49-1,Laubeel,BDBM50292627,Lozepam, Lorazepam Fabra,Delormetazepam, Temesta (TN),DTXCID303225,NSC-289758,L-230, Somagerol,Lorapam, Lorazepam Medical, Nu Pharm Brand of Lorazepam,Lorazepam solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material,Aripax, Lorazepam Nu-Pharm Brand,Azurogen,BRD-A11990600-001-01-8,(+-)-7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one,Lorzem, Llorens Brand of Lorazepam,Lorafen,DTXSID7023225, Lorazepam neuraxpharm,Lorazepan Richet, Aripax,O-Chloroxazepam; O-Chlorooxazepam; Almazine; WY 4036; WY-4036; WY4036, Lorsedal,Lorazepamum,WLN: T67 GMV JN IHJ CG IQ KR BG, Lorapam,Lorazepam Fabra, Lopam, Lorazene,Lorazepam [USAN:USP:INN:BAN:JAN],Lorazepam Lannacher,NSC289758,D00365,Lorazepam Genericon,LORAZEPAM [JAN], Quait, Sinestron,(.+/-.)-Lorazepam, Sedicepan, Orfidal Wyeth, Novo Lorazem, Lorat,Lorazepam (JP17/USP/INN), Laubeel, Sedazin, Lorazepam ct-Arzneimittel Brand,Tranqipam, Wypax, Apo-Lorazepam,Kalmalin,2H-1, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-, Lorazepam AHP Brand,LORAZEPAM [USAN], Lorazepam [USAN:INN:BAN:JAN], Rocosgen, Lorazin, Lorazepan Richet,Donix, Lorazepam Baxter Brand,GTPL5884,SMR000058410,Bonatranquan, Upan,Tolid,HMS3394H07,7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one, Punktyl, Delormetazepam,Equitam, ApoLorazepam,lorazepam,Anxira,A840886,Lorivan, Lorans,Lorazepam-Efeka,ativan,5-25-02-00248 (Beilstein Handbook Reference), Anzepam,Duralozam, (+-)-7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one,LORAZEPAM [EP MONOGRAPH], Neuraxpharm Brand of Lorazepam,CHEBI:6539,Somagerol, Stapam,2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-5-(2-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-, (+/-)-,7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one.,Wy-4036, NuLoraz, 7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-1,4-benzodiazepin-2(3H)-one,Emotival, Aplacassee, Sidenar, Lorsilan, Desitin Brand of Lorazepam,(+/-)-Lorazepam, Lorazepan Chobet, Loram,7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-benzo[e][1,4]diazepin-2(3H)-one,LORAZEPAM [USP MONOGRAPH], AHP Brand of Lorazepam,Punktyl,2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-,Loram, Lorazepam ratiopharm Brand,Lorabenz,7-chloranyl-5-(2-chlorophenyl)-3-oxidanyl-1,3-dihydro-1,4-benzodiazepin-2-one, Nu Loraz, Lorax,Lorazepam,7-Chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one (lorazepam),7-Chloro-5-(o-chlorophenyl)-1,4-benzodiazepin-2-one, Emotival,Anzepam,Nu Loraz,LORAZEPAM CIV [USP-RS], Orfidal,Rocosgen, Max Pax,Lorazepam Intensol, Lorazepam-neuraxpharm, Lorazepam Intensol, Tavor,7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepine-2-one,Trapax,Ativan, 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one,CHEMBL580,Aplacassee, Lorazepam Apotex Brand, Serra Pamies Brand of Lorazepam, Merck dura Brand of Lorazepam, Efasedan, Nu-Loraz,Sedazin,Lorazep, Apotex Brand of Lorazepam,Loridem,Aplacasse,Novolorazem, Kalmalin,AKOS015904303,DSSTox_CID_3225, Demethyllormetazepam,NCGC00159439-02,Lorazepam for system suitability, European Pharmacopoeia (EP) Reference Standard

Estimated data

Solubility: -4.218 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: No (prediction using frontiersin.org)

Addictivity Prediction: 51.8% (prediction based on www.mdpi.com)

Similitudes

Voici une série de comparaisons visant à comprendre les propriétés de ce composé. Ce site est encore très expérimental et fait l'objet d'un développement actif. Veuillez vous référer à notre série d'articles d'articles pour bien comprendre notre approche et ses limites. Ces informations sont données à titre indicatif et ne doivent pas être interprétées comme des conseils médicaux.