WHC is still in active development. Read this to understand our approach.
depiction of ZQDWXGKKHFNSQK-UHFFFAOYSA-N.svg
tripsit

hydroxyzine

Verificar en tripsit

isomerdesign

Hydroxyzine

Verificar en isomerdesign

pubchem

Hydroxyzine

Verificar en pubchem

druglab

Hydroxyzine

Verificar en druglab

drugmap

Hydroxyzine

Verificar en drugmap

wiki

Hydroxyzine

Verificar en wiki

Data

InChI: InChI=1S/C21H27ClN2O2/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-9,21,25H,10-17H2

Sinónimos: Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-, Durrax,Tox21_113569_1,HMS3604B10,AS-81900,Hychotine, 1-(p-Chlorodiphenylmethyl)-4-(2-(2-hydroxyethoxy)ethyl)piperazine,1-(p-Chloro-alpha-phenylbenzyl)-4-(2-hydroxyethoxyethyl)piperazine,Paxistil,1-(P-CHLORO-.ALPHA.-PHENYLBENZYL)-4-(2-((2-HYDROXYETHOXY)ETHYL))PIPERAZINE,BPBio1_000228,HSDB 3098, Hydroxyzine Hcl,CHEBI:5818,Aterax,Prestwick3_000133,Tox21_113569,vistaril, Atarazoid,HYDROXYZINE [HSDB],Atarax,W13117, Hidroxizina [INN-Spanish],DSSTox_GSID_23137,2-(2-{4-[(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-ethoxy)-ethanol,HYDROXYZINE [MI],2-(2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)ethanol,1-(p-Chlorodiphenylmethyl)-4-(2-(2-hydroxyethoxy)ethyl)piperazine, Atarax base,DB-049942,Hydroxyzine,2-(2-(4-(p-Chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)ethanol, Hydroxyzyne,Ethanol,2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-,Atara,Hidroxizina [INN-Spanish], Hychotine,Nevrolaks,Atarox,BDBM22875,5-23-01-00462 (Beilstein Handbook Reference),U.C.B 4492,ETHANOL, 2-(2-(4-(4-CHLORO-.ALPHA.-PHENYLBENZYL)-1-PIPERAZINYL)ETHOXY)-,C07045,Hydroxine,DB00557, 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol,neo-Calma,2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]ethanol,2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)ethanol,Placidol,Deinait,N-(4-Chlorobenzhydryl)-N'-(hydroxyethyloxyethyl)piperazine, Hydroxyzine [INN:BAN],(+/-)-HYDROXYZINE,Vistaril, Hydroksyzyny [Polish],2-[2-[4-[(4-Chlorophenyl)phenyl-methyl]piperazin-1-yl]ethoxy]ethanol,UNII-30S50YM8OG, UCB 492,SPBio_002145,Hydroxyzine (INN),Hydroxycine,CHEMBL896,HYDROXYZINE [WHO-DD],NCGC00021152-06,UCB-4492,Vesparaz-Wirkstoff,atarax,2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol,Pamazone,Idrossizina, Ataraxoid,Disron (Salt/Mix), 2-(2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)ethanol,AB00053485_25,BBL034752, Placidol,242H772,CAS-68-88-2,Hydroxyzine [INN:BAN],NCGC00018255-02, Deinait,SCHEMBL4491, 1-(p-Chloro-alpha-phenylbenzyl)-4-(2-(2-hydroxyethoxy)ethyl)piperazine, Traquizine,Ethanol, 2-[2-[4-(p-chloro-.alpha.-phenylbenzyl)-1-piperazinyl]ethoxy]-, Neo-Calma,DTXSID8023137,1-(p-Chlorobenzhydryl)-4-(2-(2-hydroxyethoxy)ethyl)diethylenediamine, Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-(9CI),1-(p-Chlorobenzhydryl)-4-[2-(2-hydroxyethoxy)ethyl]piperazine,U.c.b-4492, Hydroksyzyny, Tranquizine,HYDROXYZINE [INN],Prestwick2_000133,U.CB 4492, Paxistil, Aterax,Hydroxyzinum,Atarazoid,ETHANOL, 2-(2-(4-((4-CHLOROPHENYL)PHENYLMETHYL)-1-PIPERAZINYL)ETHOXY)-,(+/-)-,Q421937,Tran-Q,2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]ethanol,UCB 4492,NP 212,Hydroxizinum, Parenteral,Hydroxizine,DTXCID203137,30S50YM8OG,AB00053485,Hydroxyzine base,Parenteral, 1-(p-Chloro-.alpha.-phenylbenzyl)-4-[2-[(2-hydroxyethoxy)ethyl]piperazine,2-(2-(4-[(4-Chlorophenyl)(phenyl)methyl]-1-piperazinyl)ethoxy)ethanol #, Hy-Pam 25,HYDROXYZINE [VANDF],MRF-0000015,Durrax (Salt/Mix), 1-(p-Chloro-alpha-phenylbenzyl)-4-(2-hydroxyethoxyethyl)piperazine,NCGC00089816-03, 1-(p-Chlorobenzhydryl)-4-[2-(2-hydroxyethoxy)ethyl]piperazine, Atazina,GTPL7199, 1-(p-Chlorobenzhydryl)-4-[2-(2-hydroxyethoxy)ethyl]diethylenediamine,DSSTox_RID_76887,BRD-A62428732-300-03-0,HY-B0548,AKOS003334349,2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)-piperazin-1-yl)ethoxy)ethanol, U.C.B 4492,NCGC00018255-06,Ataraxoid,Hydroxyzin, Tran-Q, Plaxidol,BRD-A62428732-096-02-6, 2-(2-(4-(p-Chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)ethanol,Atarax (Salt/Mix),1-(p-Chlorobenzhydryl)-4-(2-(2-hydroxyethoxy)ethyl)piperazine,WLN: T6N DNTJ AYR&R D6& D2O2Q,L000930, Hydroxizine, Hydroxyzinum [INN-Latin], 2-[2-[4-(p-Chloro-.alpha.-phenylbenzyl)-1-piperazinyl]ethoxy]ethanol, Vesparaz-Wirkstoff,Hydroxyzine, (R),EN300-708786,BSPBio_000206, Orgatrax,(+/-)-2-(2-(4-(P-CHLORO-.ALPHA.-PHENYLBENZYL)-1-PIPERAZINYL)ETHOXY)ETHANOL,1-(p-Chloro-.alpha.-phenylbenzyl)-4-(2-((2-hydroxyethoxy)ethyl)piperazine, Idrossizina [DCIT],NCGC00018255-03,STL417960,2-[2-[4-(p-Chloro-.alpha.-phenylbenzyl)-1-piperazinyl]ethoxy]ethanol,Neurozina, Hydroxine, Hydroxyzin,Idrossizina [DCIT], UCB 4492, Neurozina, Hydroxyzine hydrochloride,MFCD00242772, N-(4-Chlorobenzhydryl)-N'-(hydroxyethyloxyethyl)piperazine,Prestwick1_000133,2-(2-(4-(p-Chloro-.alpha.-phenylbenzyl)-1-piperazinyl)ethoxy)ethanol, Vistaril, Pamazone,Hydroxyzine free base,Tranquizine,N-(4-Chlorobenzhydryl)-N'-(hydroxyethoxyethyl)piperazine, Hydroxyzinum, N-(4-Chlorobenzhydryl)-N'-(hydroxyethoxyethyl)piperazine,Plaxidol,Hydroxyzyne,AB00053485_24,1-(p-Chloro-.alpha.-phenylbenzyl)-4-[2-[(2-hydroxyethoxy)ethyl]piperazine,HYDROXYZINE [MART.],NSC 169188,NCGC00018255-04,EINECS 200-693-1,2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)ethan-1-ol,1-(p-Chlorodiphenylmethyl)-4-[2-(2-hydroxyethoxy)ethyl]piperazine,Hydroksyzyny,Hydroxyzine hydrochloride,BRN 0321392,2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)ethanol,Traquizine,HYDROXYZINE TRANQUIZINE,Hidroxizina,Ethanol, 2-(2-(4-(p-chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)-,Vistaril (Salt/Mix),Prestwick0_000133, 2-[(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethyl)oxy]ethanol, Hydroxyzine (INN), NP 212, U.CB 4492,NSC-169188, 1-(p-Chlorobenzhydryl)-4-(2-(2-hydroxyethoxy)ethyl)piperazine,1-(p-Chloro-alpha-phenylbenzyl)-4-(2-(2-hydroxyethoxy)ethyl)piperazine,1-(p-Chloro-?-phenylbenzyl)-4-[2-(2-hydroxyethoxy)ethyl)]piperazine, Hydroxyzine base,68-88-2,2-[(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethyl)oxy]ethanol,Hydroxyzinum [INN-Latin], Marex (TN),hydroxyzine, 1-(p-Chlorobenzhydryl)-4-(2-(2-hydroxyethoxy)ethyl)diethylenediamine, Hydroxycine, Nevrolaks,NSC169188, 1-(p-Chlorodiphenylmethyl)-4-[2-(2-hydroxyethoxy)ethyl]piperazine, Atarox, 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)ethanol,68-88-2 (free base),DSSTox_CID_3137,FT-0670239,1-(p-Chlorobenzhydryl)-4-[2-(2-hydroxyethoxy)ethyl]diethylenediamine,UCB 492,Hydroksisin,D08054,Atarax base, Hydroxizinum, Vistaril (TN),Ethanol, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, Hidroxizina, Atarax, Idrossizina, Atarax (TN),Atazina,Marex (TN),Hydroksyzyny [Polish]

Estimated data

Solubilidad: -2.489 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: Yes (prediction using frontiersin.org)

Addictivity Prediction: 48.2% (prediction based on www.mdpi.com)

Similitudes

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.