WHC is still in active development. Read this to understand our approach.
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Prochlorperazine

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Prochlorperazine

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Prochlorperazine

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Prochlorperazine

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Prochlorperazine

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Data

InChI: InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3

Sinónimos: 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine, Proclorperazine,RP-6140, Stemetil,A831861,Prochlorperazin,2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine, 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine,prochlorperazine, Compazine (TN),Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French],DTXSID7023514,KBioSS_002306, SKF 4657,KBio2_006456,NCI60_022783,Chlormeprazine,Prochlorpermazine,N-(gamma-(4'-Methylpiperazinyl-1')propyl)-3-chlorophenothiazine, 3-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine,RP 6140,NCGC00015856-02,10H-Phenothiazine, 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-,KBio1_000413, 3-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine, Prochlorperazine (JAN/USP/INN), 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine,BRD-K19352500-332-03-7,CHEBI:8435,Phenothiazine, 2-chloro-10-[3-(1-methyl-4-piperazinyl)propyl]-,SR-01000000260-11, Prochlorpermazine,Q2359690,Chloropernazine,Bayer A 173, Proclorperazina [INN-Spanish],Procloperazine,DB-053199,P77, Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French],Stemetil, Temetid,N-(.gamma.-(4'-Methylpiperazinyl-1')propyl)-3-chlorophenothiazine, Eskatrol,Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-,ZINC19796018,CHEMBL728,Prochlorperazine Base,MRF-0000068,KBioGR_002304, Compazine,NSC167375,Proclorperazina,058P388,KBio2_003888, Meterazine, Prochloroperazine,6140 RP,Chlormeprazin,AB00053532,Prestwick1_000399,Proclorperazina [INN-Spanish],PROCHLORPERAZINE [HSDB], Buccastem (TN), Kronocin, Emelent,YHP6YLT61T,HSDB 3171,6140 R.P., Prochlorpemazine,Prochlorpromazine, Prochlorperazine dihydrobromide,NCGC00015856-06,PROCHLORPERAZINE [VANDF], 2-Chloro-10-[3-(4-methyl-1-piper-azinyl)propyl]-10H-pheno-thiazine dimaleate,Prochlorpremazin, Prochlorperazine mesilate,NINDS_000413, 6140 RP,Prochloroperazine,Lopac-P-9178,Meterazin,SMR000653454, Vertigon,Prochlorperazine [USP:INN:BAN:JAN],STL371212,Spectrum_000840,Spectrum4_000972,Opera_ID_244,NCGC00015856-03,NCGC00015856-04,Temetid,PROCHLORPERAZINE [ORANGE BOOK],Buccastem,PROCHLORPERAZINE [JAN],MLS001148133,KBio2_004872,FT-0603243,Prestwick2_000399,Prochlorperazine mesylate, 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine,Vertigon,Nipodal, Prochlorperazine [USAN:INN:BAN:JAN],EINECS 200-379-4,Compro,Prestwick3_000399,DB00433,Compazine, N-(gamma-(4'-Methylpiperazinyl-1')propyl)-3-chlorophenothiazine, Nipodal,AB00053532_29,CCG-205112, Prochlorperazine Edisylate Salt,D00493, Compazine Suppositories,Spectrum3_000881,SPBio_002538, Prochlorperazinum [INN-Latin], Stemzine (TN),2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine,2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine #,MLS000028600,Compazine (*Maleate*),CAS-84-02-6,L001030, Compro,SBI-0051005.P004,PROCHLORPERAZINE [INN],Spectrum2_001297,58-38-8,cMAP_000013,10H-Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-,PROCHLORPERAZINE [MI],Prochlorperazine maleate,KBioSS_001320, Proclorperazina, Meterazin,Prochlorperazinum [INN-Latin],Proazine,NCGC00015856-01,Compazine Suppositories, Compro (TN),UNII-YHP6YLT61T,SPBio_001333,PROCHLORPERAZINE [MART.], Phenotil (TN),PROCHLORPERAZINE [USP MONOGRAPH],BSPBio_000617,Kronocin,Probes1_000265,C16030,2-chloro-10-[3-(4-methylpiperazino)propyl]phenothiazine;ethane-1,2-disulfonic acid,KBio3_002784,2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine, Procloperazine,Capazine,3-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine,Chlorperazine,Tementil, P77,PROCHLORPERAZINE [WHO-DD],2-Chloro-10-(3-(1-methyl-4-piperazinyl)-propyl)-phenothiazine,Emelent,Compro (TN),BDBM78434,Prochlorperazine (JAN/USP/INN),SMR000058705,AB00053532_30,KBio3_001762, RP 6140,KBio2_001320, 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine,NCGC00015856-16,CHLOPERAZINE, 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-10H-phenothiazine,Prochlorpemazine, Prochlorperazine dimaleate,3-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine,Phenothiazine, 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-,Procloropromazina,cid_91499,BSPBio_002394, Bayer A 173,MLS006011830, Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine,Eskatrol (Salt/Mix), Chlormeprazine,IDI1_000413,Lopac0_001034,BPBio1_000679,AKOS003600762,GTPL7279, Prochlorperazine maleate,2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid,Prochlorperazine, Prochlorperazin,HMS2231P21,2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine,C07403,Proclorperazine,Meterazine, Compazine (*Maleate*),NCGC00015856-05,Prestwick0_000399,NSC17478,SKF 4657,SCHEMBL18429,NCGC00015856-07, Prochlorpromazine,Proclorpemazina,SDCCGSBI-0051005.P005,BRD-K19352500-070-05-8,2-chloro-10-(3-(4-methylpiperazin-1-yl)propyl)-10h-phenothiazine,NCGC00023036-03,2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine;ethane-1,2-disulfonic acid,KBioGR_001343, Combid,Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine,KBio2_002304, Novamin, Prochlorperazinum,10H-PHENOTHIAZINE, 2-CHLORO-10-(3-(4-METHYL-1-PIPERAZINYL)PROPYL, Stemetil (TN), Tementil,Spectrum5_001339, Capazine,Prochlorperazinum, Chlorperazine,Probes2_000307,DivK1c_000413,KBio2_007440,EN300-708775,2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine,2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-10H-phenothiazine,BRD-K19352500-070-02-5


Estimated data

Solubilidad: -3.635 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: Yes (prediction using frontiersin.org)

Addictivity Prediction: 25.9% (prediction based on www.mdpi.com)

Similitudes

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.