WHC is still in active development. Read this to understand our approach.
depiction of PHVGLTMQBUFIQQ-UHFFFAOYSA-N.svg
isomerdesign

Nortriptyline

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pubchem

Nortriptyline

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drugmap

Nortriptyline

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wiki

Nortriptyline

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Data

InChI: InChI=1S/C19H21N/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19/h2-5,7-11,20H,6,12-14H2,1H3

Sinónimos: KBio3_001611,KBioSS_001521,Nortriptilina [DCIT], 5-(alpha-Methylaminopropylidene)dibenzo(a,d)cyclohepta(1,4)diene,KBio2_004089,PDSP1_001805,AMITRIPTYLINE HYDROCHLORIDE IMPURITY C [EP IMPURITY],NSC78248,SPBio_001093,NCI-169453,BRN 2216786,ZINC1530741,Nortrilen, Allegron,Noramitriptyline,NCGC00024261-03,PDSP2_001788,Spectrum2_000997,Demethylamitriptyline,nortriptylina,NCGC00014483-23,EINECS 200-788-8, Nortriptilina,Pamelor,SDCCGSBI-0050843.P006, Sensival Ventyl,BSPBio_002111,Avantyl, 10,11-Dihydro-5-(3-methylaminopropylidene)-5H-dibenzo(a,d)(1,4)cycloheptene,Sesaval,Demethylamitriptylene, 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine, Desmethylamitriptylin, Sesaval,5-(3-(Methylamino)propylidene)dibenzo(a,e)cyclohepta(1,5)diene,BL03SY4LXB, NCI169453,D08288,methyl({3-[(2E)-tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene]propyl})amine,nortriptyline, Pamelor (TN),Prestwick2_000254,Spectrum5_001377,Q61387,KBioGR_000870,Aventyl;Desitriptilina, Nortriptyline (INN),Pamelor hydrochloride,EN300-57709, Desitriptilina,BDBM112777,DB00540,NCGC00014483-08, Nortriptyline [INN:BAN],UNII-BL03SY4LXB, Nortryptyline,Desitriptilina, Allegron (TN),Lumbeck,SPBio_002287,10,11-Dihydro-5-(3-methylaminopropylidene)-5H-dibenzo(a,d)(1,4)cycloheptene,BSPBio_000068,KBio1_000151,NCGC00014483-07,NCGC00014483-10,Desmethylamitriptyline,HMS1920B20,methyl(3-{tricyclo[9.4.0.0,3,8]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)amine, Desitriptyline,Nortryptyline,Prestwick3_000254, 3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methylpropylamine,AB00052061_16,Aventyl,Psychostyl,CAS-894-71-3,DivK1c_000151, Demethylamitriptyline,NCGC00024261-05,Nortriptylinum,NCGC00014483-11,10,11-Dihydro-5-(3-methylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptene, 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine,NORTRIPTYLINE [VANDF],QTL1_000063,N-Methyl-3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yliden)propylamin,Nortrilen (TN),NORTRIPTYLINE [WHO-DD],KUC112478N,72-69-5,Noritren,Sensaval,CCRIS 9175,10,11-Dihydro-N-methyl-5H-dibenzo(a,d)cycloheptane-.DELTA.,.gamma.-propylamine,GTPL2404,1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-, Demethylamitriptylene, 5-(3-(Methylamino)propylidene)dibenzo(a,e)cyclohepta(1,5)diene,Demethylamitryptyline,Nortriptylene hydrochloride,NCIStruc1_000856,NCGC00014483-12,10,11-DIHYDRO-N-METHYL-5H-DIBENZO(A,D)CYCLOHEPTENE-D(SUP5,.GAMMA.)-PROPYLAMINE,5-[3-(Methylamino)propylidene]dibenzo[a,E]cyclohepta[1,5]diene, Altilev,Spectrum_001041,SPECTRUM1500442,NCGC00014483,methyl({3-[(2E)-tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]propyl})amine,Triptyline-M nor,N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine,NCIOpen2_004361,Nortriptyline (INN),DTXSID9023384,AB00052061,5H-Dibenzo[a,d]cycloheptene-.DELTA.5,.gamma.-propylamine, 10,11-dihydro-N-methyl-,3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methylpropylamine, Nortriptilina [DCIT],NCGC00014483-09,SR-01000000223-4, Nortriptylene hydrochloride,NORTRIPTYLINE [INN],CS-0067638, Pamelor hydrochloride,Pharmakon1600-01500442,SCHEMBL34527,NSC 757234,NCGC00014483-02,5-(3-Methylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene,Spectrum3_000526,CHEBI:7640,(2)10,11-Dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-.delta.5.gamma.-propylamine,N-Methyl-3-(10,11-dihydro-5H-dibenzo[a,d]cycloheptan-5-ylidene)propylamine,HY-118620,Nortriptylinum [INN-Latin], Nortriptylinum [INN-Latin],NSC169453,3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine,Acetexa,NINDS_000151, Sensoval (TN),Lopac-N-7261, Psychostyl,21B,Amitryptyline, demethyl-, Nortrilen (TN),KBio2_006657,KBio2_001521,MRF-0000480,KSC-315-028-,US8629135, SW-02, Sensaval, Pamelor, Noritren,3-(10,11-DIHYDRO-5H-DIBENZO(A,D)(7)ANNULEN-5-YLIDENE)-N-METHYLPROPAN-1-AMINE, Aventyl,Nortriptyline,NSC-757234, Aventyl (TN),NCGC00014483-03,Ateben,1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methyl-, Lumbeck,NCGC00024261-06,3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methylpropylamine, Nortrilen, Nortryptiline, 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Delta(5,gamma)-propylamine,Nortriptyline [INN:BAN],Prestwick0_000254,NCGC00014483-04,Psychostyl (Salt/Mix),NORTRIPTYLINE [MI],CCG-38266,NCGC00014483-05,5-(alpha-Methylaminopropylidene)dibenzo(a,d)cyclohepta(1,4)diene,NCI60_001354,NCGC00024261-04,C07274,NCGC00014483-14,BIDD:PXR0187, 10,11-Dihydro-N-methyl-5H-dibenzo(a,d)cycloheptene-delta(5,gamma)-propylamine,Prestwick1_000254,10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Delta(5,gamma)-propylamine,HMS500H13,3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine, Noramitriptyline, (2)10,11-Dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-.delta.5.gamma.-propylamine, AVENTYL HCL, 5-(3-Methylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene,NCIStruc2_000700,3-(5,6-dihydrodibenzo[[?],[?]][7]annulen-11-ylidene)-N-methyl-propan-1-amine,IDI1_000151, Desmethylamitriptyline, Norpress (TN),Nortryptiline,NSC757234,NCGC00014483-16,Lopac0_000868,Nortriptilina,SBI-0050843.P004, Ateben,NCI169453,BPBio1_000076,CHEMBL445,NCGC00014483-06, Avantyl, N-Methyl-3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yliden)propylamin, Demethylamitryptyline,10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Delta5,gamma-propylamine,Spectrum4_000455,5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N-methyl-, Vividyl,BRD-K91263825-003-03-2, Nortriptylinum,HMS2091J20,10,11-Dihydro-N-methyl-5H-dibenzo(a,d)cycloheptene-delta(5,gamma)-propylamine,HSDB 3371

Estimated data

Solubilidad: -3.771 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: Yes (prediction using frontiersin.org)

Addictivity Prediction: 53.2% (prediction based on www.mdpi.com)

Similitudes

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.