WHC is still in active development. Read this to understand our approach.
depiction of PHEDXBVPIONUQT-UHFFFAOYSA-N.svg
tripsit

pma

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psychonaut

PMA

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pubchem

Phorbol 12-myristate...

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druglab

PMA

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drugmap

phorbol 12-myristate...

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Data

InChI: InChI=1S/C36H56O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3

Sinónimos: DTXSID5023798,Myristic acid, 9-ester with 1,1aalpha,1bbeta,4,4a,7aalpha,7b,8,9,9a-decahydro-4abeta,7balpha,9beta,9aalpha-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8alpha-tetramethyl-5H-cyclopropa(3,4)benz(1,2-e)azulen-5-one 9a-acetate, (+)-,Phorbol ester,Bio2_000352,phorbol 13-acetate 12-myristate,AKOS024418767,DivK1c_006897,HY-18739,Spectrum4_000889,Phorbol monoacetate monomyristate,SpecPlus_000801,TPA (phorbol derivative),Bio1_000789,N2060,SCHEMBL115567,TPA,KBio3_000708,Spectrum2_001911,CHEMBL279115,HB0502,Spectrum5_001855,NI40JAQ945,(1S,2S,6R,10S,11R,13S,14R,15R)-13-(acetyloxy)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.0^{2,6}.0^{11,13}]pentadeca-3,8-dien-14-yl tetradecanoate,SPECTRUM330004,KBio2_000364,12-O-Tetradecanoyl phorbol acetate,Bio1_000300,Myristic acid, 9-ester with 1,1aalpha,1bbeta,4,4a,7aalpha,7b,8,9,9a-decahydro-4abeta,7balpha,9beta,9aalpha-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8alpha-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5,Phorbol 12-myristate 13-acetate (PMA),4abeta,7aalpha,7balpha,8alpha,9beta,9aalpha)]-,NSC 262244,GTPL2341,KBioGR_001298,(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(Acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl tetradecanoate, tetradecanoyl-beta-phorbol acetate,NCGC00161633-04,Phorbol 12-tetradecanoate 13-acetate,4-.beta.-Phorbol 12-myristate 13-OAc,Phorbol 12-myristate 13-acetate diester,5H-Cyclopropa(3,4)benz(1,2-e)azulen-5-one, 1,1a-beta,1b-alpha,4,4a,7a-beta,7b,8,9,9a-decahydro-4a-alpha,7b-beta,9-alpha,9a-beta-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-beta-tetramethyl-, 9a-acetate 9-myristate,Phorbol-12-myristate-13-acetate - CAS 16561-29-8,1H-Cyclopropa[3,4]benz[1,2-e]azulene, tetradecanoic acid deriv.,Phorbol-myristate acetate,KBio2_002932,CHEBI:37537,UNII-NI40JAQ945,Tetradecanoic acid, 9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9, 9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa(3,4)benz(1,2-e)azulen-9-yl ester, (1aR-(1aa,1bb,4ab,7aa,7ba, 8a,9b,9aa))-,NSC-262644,Pma (phorbol ester),BDBM50099066,HMS3403D05,NSC262244,Tpa (phorbol ester),Cocarcinogen C3,SPBio_001902,HSDB 3542,Q416716,Tetradisant-[[4-(1, 1-oxideomega.-[2-(dodecylthio)ethoxy]-,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-, mixt. with denatured calf thymus DNAA, (2S-cis)-, compd. with sulfinylbis[methane] (2:1)2S-cis)-1:9),MFCD00036736,Cocarcinogen A1,Tetradecanoic acid, 9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester, [1aR-(1aalpha,1bbeta,,BRN 2407201,Phorbol myristate acetate,12-o-tetradecanoyl phorbol-13-acetate,11016-13-0,12-Tetradecanoylphorbol 13-acetate,BCBcMAP01_000182,Bio2_000832,5H-Cyclopropa(3,4)benz(1,2-e)azulen-5-one, 1,1a-beta,1b-alpha,4,4a,7a-beta,7b,8,9,9a-decahydro-4a-alpha,7b-beta,9-alpha,9a-beta-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-beta-tetramethyl-, 9a-acetate 9-m,NSC262644,[acetoxy-dihydroxy-(hydroxymethyl)-tetramethyl-oxo-[?]yl] tetradecanoate,Bio1_001278,12-o-tetradecanoylphorbol-13-acetate (tpa),12-o-tetradecanoyl-phorbol-13-acetate,13-O-Acetylphorbol 12-myristate,W-201494,EX-A6920,beta-Phorbol 12-myristate 13-acetate,BRD-K68552125-001-03-8,CCRIS 716,12-o-Tetradekanoylphorbol-13-acetat,UPCMLD-DP069,UPCMLD-DP069:002,ZINC8214783,Myristic acid, 9-ester with 1,1a-alpha,1b-beta,4,4a,7a-alpha,7b,8,9,9a-decahydro-4a-beta,7b-alpha,9-beta,9a-alpha-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-alpha-tetramethyl-5H-cyclopropa(3,4)benz(1,2-e)azulen-5-one, 9a-acetate,PMA,(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl tetradecanoate,PHORBOL 12-MYRISTATE 13-ACETATE DIESTER [MI],s7791,FS-4842,tetradecanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9,PMA, for use in molecular biology applications, >=99% (TLC),12-O-tetradecanoyl phorbol-13-acetate;Cocarcinogen A1; Cocarcinogen C3,PMA (tumor promoter),Phorbol-12-myristate 13-acetate,Factor A1,HMS1792D05,CCG-39863,NSC-262244,C05151,phorbol12-myristate13-acetate,NCGC00161633-01,KBioSS_000364,phorbol-12-myristate-13-acetate,12-O-Tetradecanoylphorbol-13-acetate,P1585,HMS1990D05,Phorbol 12-myristate 13-acetate, synthetic, >=98.0% (TLC),AC-33957,KBio1_001841,12-Tetradecanoylphorbol-13-acetate,MolMap_000041,(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(Acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a ,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl tetradecanoate,KBioGR_000364,NCGC00161633-05,NSC626496,Phorbol 12-myristate 13-acetate, >=99% (TLC), film or powder,BRD-K68552125-001-04-6,KBio3_000707,[(1S,2S,6R,10S,11R,13S,14R,15R)-13-acetyloxy-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-14-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] tetradecanoate,yristate,CS-6053,12-Tetradecanoylphorbol 13-monoacetate,NSC-626496,12-O-TETRADECANOYLPHORBOL-13-ACETATE [HSDB],LMPR0104330002,16561-29-8,13-Tetradecanoylphorbol acetate,12-O-Tetradekanoylphorbol-13-acetat [German],Tetradecanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester,Pentahydroxy-tigliadienone-monoacetate(c)monomyristate(b),IDI1_002107,Phorbol acetate, myristate,BIDD:PXR0145,BSPBio_001024,UPCMLD-DP069:001,tetradecanoyl-beta-phorbol acetate, 12-O-tetradecanoylphorbol-13-acetate,PHORBOL-12-TETRADECANOYL-13-ACETATE,Phorbol 13 Acetate 12 Myristate,12-O-Tetradecanoylphorbol 13-acetate,KBio2_005500,CBiol_002014,Tetradecanoic acid, 9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa(3,4)benz(1,2-e)azulen-9-yl ester, (1aR-(1aalpha,1bbeta,4abeta,7aalpha,7balpha,8alpha,9beta,9aalpha))-,4beta-Phorbol 12-myristate 13-acetate,HMS1362D05,Phorbol 12-myristate 13-acetate,Tetradecanoylphorbol acetate,4beta-Phorbol-12-myristate-13-acetate,Factor A1 (croton oil)


Estimated data

Solubilidad: -6.198 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: No (prediction using frontiersin.org)

Addictivity Prediction: 26.5% (prediction based on www.mdpi.com)

Similitudes

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.