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isomerdesign

Loratadine

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pubchem

Loratadine

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Loratadine

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Loratadine

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Data

InChI: InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3

Sinónimos: LORATADINE [USP-RS],Loratadine Redidose,Loratidine,NCGC00261365-01,Bonalerg,Loratadinum [Latin],KBio2_001976, Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylate,Polaratyne, Roletra (TN),Spectrum3_000740,HMS3393G11, Sch 29851, Clarityne-D,NSC758628,HMS3412N06, 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-, ethyl ester, 4-(8-Chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester,NC00036,IDI1_000792,Q424049,KBioGR_000693,Loradex, L 9664, Rinomex,Clarityne,Tox21_500680,SCHEMBL4596,Bactimicina allergy,1-Piperidinecarboxylic acid,4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester, Talorat Dy, Claritin, Biloina,NCGC00015619-11,Klaritin, Fristamin, Claratyne,Restamine, Alarin,HSDB 3578,KS-1079, Versal,L0223,Claritin Hives Relief, Loratadinum [Latin], Rinolan (TN),NSC-758628, Lowadina, Lomilan (TN),NCGC00023125-02,Claritin, Claritin D,Lorfast,Lowadina,FT-0627976,LORATADINE [VANDF],8-chloro-11-(1-ethoxycarbonyl-4-piperidylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine,MLS001423984,NCGC00023125-05, Alavert, Claritin, Loratadine, Loratadine Wyeth Brand,SR-01000075968-6,Claritin Hives Relief Reditab,Anhissen, Loranox,NCGC00015619-01, Loradif,1398065-63-8,Lergy, Restamine,LoratadineI-p25,Spectrum5_001650,MLS000069647,Claritin Reditabs,Opera_ID_1868,Loratadine, United States Pharmacopeia (USP) Reference Standard,Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylate, Loraver,Q-100833, Clarityn (TN),Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidine)-1-piperidinecarboxylate, 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester,Sohotin,SY052751,NCI60_041473,EN300-119520,LORATADINE [EP MONOGRAPH], Anhissen,8-chloro-6,11-dihydro-11-(1- ethoxycarbonyl-4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, Histaloran,Sanelor,loratadine impurity c;4-(4,8-dichloro-5,6-dihydro-11h-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester,NCGC00015619-06,CLARITIN-D COMPONENT LORATADINE,CHEBI:6538,Loratadine 0.1 mg/ml in Methanol,Tox21_110185_1, Clarityne Dy Repetabs,ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene}piperidine-1-carboxylate, Loratadinum, Children's Claritin, Bonalerg,KBio2_007112,Loritine,BCP0726000007,LoratadineI-m100(L13),HMS2051G11,11-[N-(ethoxycarbonyl)-4-piperidylidene]-8-chloro-6,11-dihydro-5H-benzo-[5,6]cyclohepta[1,2-b]pyridine,Clarityn,BRD-K82795137-001-10-6,Velodan,DSSTox_CID_3224, Sensibit,4-(8-chloro-5,6-dihydrobenzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylic acid ethyl ester,Pharmakon1600-01503712, Sanelor, Claritin (TN), Claritine,NSC-721075,Lesidas, Zeos,LORATADINE [MI],Sch-29851,BIDD:GT0198,LORATADINE COMPONENT OF CLARITIN-D, 1-piperidinecarboxylic acid,4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-,ethyl ester,Lisino,Lorantis,EU-0100680,NCGC00015619-10, Tadine,Civeran, Sch-29851,loratadine, AllergyX (TN),Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate,HY-17043, Civeran, Claritin reditab,ACT04775,LORATADINE [ORANGE BOOK],Flonidan,LORATADINE [INN], 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acidethyl ester, Flonidan (TN),NCGC00015619-03,Loraver,BL164637, Alavert (TN),4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cycloheptal[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester, Lertamine, Sinhistan Dy,LoratadineI-p80(L13),MLS001148466, Clarityn, Fristamin (TN),Spectrum_001496, Clarityne, Alavert,DivK1c_000792,NCGC00023125-06,AKOS005499513,SW197416-3,KBio1_000792, 1-Piperidenecarboxylic acid, 4-(8-chloro-5,6-duhydro-11H-benzo [5,6]cyclohepta[1,2-b]-pyridin-11-ylidene)-, ethyl ester,CCG-39362,NCGC00015619-07,NCGC00015619-09,Versal,AB06849, Claritin Reditabs,LORATADINE [HSDB],Children's Claritin,NINDS_000792, Optimin,BCP22338,AC-2086,Loratadine- Bio-X,LoratadineI-m173(L13),LP00680,Claratyne,Clarityne Dy Repetabs,794L755,SDCCGSBI-0050659.P004,Loratadine (JAN/USP/INN),REGID_for_CID_3957, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cycloheptal[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester,ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate,Allertidin,BAY76-2211,SPECTRUM1503712,L000667, Sch29851,SR-01000075968,HMS3654L17, Clarium,BCP9000858,AMY15355,NCGC00015619-05,Loratadine,Lopac-L-9664, Loratadine (JAN/USAN/INN),NCGC00255171-01,AB00053224_18,HMS2093I15,DTXSID2023224, Pylor,Loratadine [USAN:USP:INN:BAN], Wyeth Brand of Loratadine,Claritine,CS-0887,KBio3_001520,NSC 721075,Clarinase Reperabs,Claritin reditab,HMS2235G23,LORATADINE [WHO-DD],SBI-0050659.P003,Lertamine,Z1521553845,Zeos, Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate,loratadine-form1,Bedix Loratadina,CAS-79794-75-5,Loratadinum, Claritin Hives Relief Reditab, Clarityne (TN), Velodan,SR-01000075968-4,SR-01000075968-1,HMS3676N06,SPBio_001548, Clarinase,Sch 29851,Biloina,Tocris-1944,CHEMBL998,HMS2090O18,SR-01000075968-3,Tox21_301532,LORATADINE [EP IMPURITY],1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester,NCGC00023125-07,HMS502H14,D00364,DL-436,1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-, ethyl ester,Loradif,Pylor,Clarityne-D, Polaratyne,Nularef,HMS3714E09, Loratadina [Spanish],Cronopen,DSSTox_RID_76931,NCGC00023125-04,HMS3268M16,ZINC537931,NSC721075,Histaloran,Oprea1_027965,Loratadine, European Pharmacopoeia (EP) Reference Standard,ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0,3,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene}piperidine-1-carboxylate, Claritine (TN),Sinhistan Dy,AB00053224-16,KBioSS_001976,Optimin,Tadine,Loratadine, British Pharmacopoeia (BP) Reference Standard,Talorat Dy,NCGC00015619-08, Claratyne Cold,NSC 758628,NCGC00015619-04,Lorastine,STK574925,NCGC00015619-13, Claritin Hives Relief,4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine-1-carboxylic acid ethyl ester,Loranox,Alerpriv,MLS000758260,Loratadina [Spanish],MFCD00672869,Spectrum2_001584, Lorantis,ethyl 4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidine-1-carboxylate, Allertidin, Rhinase,7AJO3BO7QN, Loritine,AB00053224-15,Loratadine for system suitability, European Pharmacopoeia (EP) Reference Standard, Lorfast,NCGC00015619-12,Fristamin,Loratyne,LoratadineI-0deg(L13),HMS3371D13,LORATADINE [USP MONOGRAPH],Loratadine, >=98% (HPLC), powder,GTPL7216, Loratyne, Lisino,Tox21_110185,DSSTox_GSID_23224, Tidilor (TN),KBio2_004544,CCG-100786,Topcare childrens allergy relief,Claritin (TN), Loratadine Redidose,79794-75-5, Bedix Loratadina, Lergy,Loratadina,8-Chloro-6,11-dihydro-11-(1-ethoxycarbonyl-4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine,L 9664,UNII-7AJO3BO7QN,Loratadine,(S),loratadine-form2-He,DB00455, Loratidine,LORATADINE [JAN], Lorastine,Sensibit, Symphoral (TN),Loratadine (Desloratadine Impurity E),ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate,BBL010757,LORATADINE [USAN],Alavert,LORATADINE [MART.],NCGC00015619-02, Loradex,BRD-K82795137-001-02-3,ethyl-4-(8-chloro-5,6-dihydro-11H-benzo-[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate, Nularef, Lorfast (TN),Aerotina,SMR000058255,AB00053224_17, Alerpriv, Lesidas,BSPBio_002300,BDBM22876,Lopac0_000680,HMS3262G21,NCGC00015619-26, Roletra, Loratadine [USAN:BAN:INN], Loratadina,Loratadine, Pharmaceutical Secondary Standard; Certified Reference Material,s1358, Clarinase Reperabs, Claratyne Decongestant,Spectrum4_000177,1-Piperidenecarboxylic acid,6-duhydro-11H-benzo [5,6]cyclohepta[1,2-b]-pyridin-11-ylidene)-, ethyl ester,Loracert,Loratadine-d5(ethyl-d5), Sohotin, Loracert,4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester

Estimated data

Solubilidad: -6.038 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: Yes (prediction using frontiersin.org)

Addictivity Prediction: 22.0% (prediction based on www.mdpi.com)

Similitudes

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.