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isomerdesign

Papaverine

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pubchem

Papaverine

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drugmap

Papaverine

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wiki

Papaverine

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Data

InChI: InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3

Synonyms: 4-[(6,7-Dimethoxyisoquinolyl)methyl]-1,2-dimethoxybenzene,papaverine,Prestwick3_000583,Mesotina (TN), Dilaves (TN),AB00053515_14,PAPAVERINE [VANDF],KBio2_003039, Cerespan (TN),BRN 0312930,PAPAVERINE [MART.], Pavacen (TN), Papaverine chlorohydrate, Pavakey (TN),PAPAVERINUM [HPUS],Isoquinoline,7-dimethoxy-1-veratryl-, Pavarine, 58-74-2,Cerespan, Pap-Kaps-150 (TN),Lopac-P-3510, Paverolan (TN), Spasmo-Nit (TN), Papalease (TN),ZINC56555, RS 47,ACon1_000238,AB00053515, 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline, Drapavel,UNII-DAA13NKG2Q, Ro-Papav (TN), Qua bid (TN), 1-[(3,4-Dimethoxyphenyl)methyl]6,7-dimethoxyisoquinoline, Paptial TR (TN),Robaxapap,DivK1c_000321,BDBM14754,PAPAVERINE [MI],Papaverinum,SPBio_002645,CHEBI:28241, 6,7-Dimethoxy-1-(3,4-dimethoxybenzyl)isoquinoline,SBI-0050931.P004, Cardioverina (TN), Paverolan,MEGxp0_001880, Papacon, Vasal (TN),NCGC00015810-03, Papalease,NSC136630, Papanerin-hcl (TN),Pavacot, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline, Papaverin,1-{[3,4-bis(methyloxy)phenyl]methyl}-6,7-bis(methyloxy)isoquinoline, Papaversan (TN),6,7-Dimethoxy-1-(3,4-dimethoxybenzyl)isoquinoline,DAA13NKG2Q, Durapav (TN),BSPBio_000426, Papaverina,Spectrum3_000537, Pavacap (TN), Papaverina [Italian], 4-[(6,7-Dimethoxyisoquinolyl)methyl]-1,2-dimethoxybenzene, Pavacap, Vasal,Prestwick0_000583, S-M-R, Papaverine monohydrochloride,DB-053252, Forpaven (TN), Pavatest,ALBB-010475,KBio3_001653,NCGC00015810-01,NCGC00015810-29, Pavabid (TN),NSC35443, Papital TR (TN),NINDS_000321,1-(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline, Alapav, Drapavel (TN),Isoquinoline, 1-((3,4-dimethoxyphenyl)methyl)-6,7-dimethoxy-,Spectrum4_000467,KBioSS_000471,1-(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline #,Spectrum2_000978,SPBio_001015, Paverina (TN),NOSCAPINE IMPURITY A [EP IMPURITY], Papanerin,NSC 136630, Papaverin-Hamelin (TN),Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-,Papaverine [BAN], Paptial TR,Spectrum_000071, Pameion (TN), Dilaves,KS-5336, PAP H,Papaverine (BAN), Optenyl (TN), 1-((3,4-Dimethoxyphenyl)methyl)-6,7-dimethoxyisoquinoline,Papaverin, TNP00305, Papaverine (BAN),Ceraspan,EV1, Opdensit (TN), Pavatine, Ceraspan, Durapav,BRD-K15567136-003-18-1,HMS3746M21, Myobid (TN), Pavadel (TN), Paveron,CS-7800,1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline,Isoquinoline, 6,7-dimethoxy-1-veratryl-,58-74-2 (free base),DTXSID4023418, Papaverinium chloride, 1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXYISOQUINOLINE, Isoquinoline,6,7-dimethoxy-1-veratryl-(8CI),BPBio1_000470, Papanerine, Delapav,STK039035,D07425, Pavnell (TN), Pavacen,Isoquinoline, 6,7-dimethoxy-1-veratryl-(8Cl), Isoquinoline, 6,7-dimethoxy-1-veratryl-,BSPBio_002153, Pavabid Hp, Cardiospan (TN),SR-01000003098-10, Paveron (TN),NCGC00015810-02,6,7-Dimethoxy-1-veratrylisoquinoline,2wey, Vaso-Pav (TN), Qua bid, Pavacels,5-21-06-00182 (Beilstein Handbook Reference),NCGC00015810-09, Pavatym,Spectrum5_001188, Pameion,NCGC00015810-06,Papaverine,Prestwick1_000583, Papanerin-hcl,Papaverine 100 microg/mL in Acetonitrile,Oprea1_387689,KBioGR_000914, Cerebid (TN), Myobid, 1-{[3,4-bis(methyloxy)phenyl]methyl}-6,7-bis(methyloxy)isoquinoline,BBL012345, Dicertan (TN), Genabid, Forpavin,1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline, Pavacot,1-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline, Dynovas, Pavagen (TN),1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-isoquinoline, Pavabid, 6,7-Dimethoxy-1-veratrylisoquinoline,Oprea1_810508, Chlorhydrate de papaverine, Cardoverina,IDI1_000321, Robaxapap,6,7-dimethoxy-1-veratryl-isoquinoline;hydrochloride,EN300-177755, Houde (TN),DB01113, Pavnell,Q410374, Isoquinoline, 6,7-dimethoxy-1-veratryl-(8Cl), Papacon (TN), Panergon (TN),NCGC00015810-24,HY-18077,BRD-K15567136-001-01-1,BRD-K15567136-003-06-6, Dispamil,NCGC00015810-07, Cerebid, Pavatest (TN),S-M-R, Therapav (TN),Papaverina [Italian],HMS3561N11,SDCCGSBI-0050931.P005, Vasospan (TN), Dispamil (TN), UNII-DAA13NKG2Q,KBio2_000471, Papavarine chlorhydrate, Delapav (TN),NCGC00015810-05,Pavabid, Pamelon (TN),1-[(3,4-Dimethoxyphenyl)methyl]6,7-dimethoxyisoquinoline,NCGC00015810-08,Papanerin, Papaverine [BAN], Alapav (TN),Isoquinoline,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-, Mesotina (TN),Papaverina, Papaverine Hcl, Pavagen,TNP00305, Cepaverin (TN),NCI60_003183, Cardiospan, NSC 136630,NSC-136630,PAPAVERINE [WHO-DD],AKOS000277460, Vaso-Pav,NCGC00024428-03,Papanerine,6,7-DIMETHOXY-1-(3.4-DIMETHOXYBENZYL)-ISOQUINOLINE,EINECS 200-397-2,ACon1_002094,58-74-2,Prestwick2_000583,Papaverine free base, Pavased (TN),CCG-202821, Papital TR,NCGC00015810-04,KBio1_000321, Pavadyl (TN), Dynovas (TN),NCGC00024428-04, Albatran (TN), Artegodan (TN),1-((3,4-Dimethoxyphenyl)methyl)-6,7-dimethoxyisoquinoline,RS 47, Papaversan,SDCCGMLS-0003037.P003,Lopac0_000957, 1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-isoquinoline, Panergon, Pamelon,NCGC00015810-13,KBio2_005607,C06533,CHEMBL19224, Mesotina,WLN: T66 CNJ B1R CO1 DO1& HO1 IO1, Cerespan, Ro-Papav,CAS-61-25-6,HSDB 3147,SCHEMBL34702

Estimated data

Solubility: -4.898 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: Yes (prediction using frontiersin.org)

Addictivity Prediction: 56.3% (prediction based on www.mdpi.com)

Similarities

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.