WHC is still in active development. Read this to understand our approach.
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isomerdesign

Cevimeline

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pubchem

Spiro(1-azabicyclo(2...

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drugmap

Cevimeline

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Cevimeline

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Data

InChI: InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3

Synonyms: AF-102B,(3S,2'S)-2'-Methylspiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], SND-5008, (+/-)-cis-2-methylspiro(1-azabicyclo[2.2.2]octance-3,5'-(1,3)oxathiolane) hydrochloride hemihydrate,NCGC00371104-01, Cevimeline hydrochloride, AF 102B, FKS-508, SNI-2011, (2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane] hydrate hydrochloride, Cevimeline HCl 1/2H2O,Cevimeline [INN],107233-08-9,CEVIMELINE [WHO-DD], 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine, Evoxac (TN),SCHEMBL299761, Cevimeline [INN], Saligren, (2R,2'R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] dihydrochloride hydrate, Cevimeline hydrochloride [USAN], Cevimeline hydrochloride hydrate, Cevimeline hydrochloride hydrate (JAN), AF102B,K9V0CDQ56E, Cevimeline.HCl, Cis-2-Methylspiro(1,3-oxathiolane-5,3')quinuclidine hydrochloride hydrate (2:2:1), SNK-508, Cevimeline (INN), Saligren (TN), Fks 508,CEVIMELINE [VANDF], (2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane] dihydrate hydrochloride, Cevimeline hydrochloride hemihydrate, Cevimeline hydrochloride (USAN),HSDB 7286,UNII-K9V0CDQ56E,CEVIMELINE [MI], (2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane] hydrate dihydrochloride,Fks 508,Spiro(1-azabicyclo(2.2.2)octane-3,5'-(1,3)-oxathiolane), 2'-methyl-, cis-,ZINC8699,Evoxac,Cevimeline, SND 5008, AF-102B, FKS-508, AF-102B, (2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane],CEVIMELINE [HSDB],AKOS006327909,SPIRO(1-AZABICYCLO(2.2.2)OCTANE-3,5'-(1,3)OXATHIOLANE), 2'-METHYL-, (+-)-cis-2-Methylspiro(1,3-oxathiolane-5,3'-quinuclidine) hydrochloride, hemihydrate

Estimated data

Solubility: -1.248 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: No (prediction using frontiersin.org)

Addictivity Prediction: 44.5% (prediction based on www.mdpi.com)

Similarities

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.