WHC is still in active development. Read this to understand our approach.
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isomerdesign

Phenylephrine

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pubchem

Phenylephrine

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Phenylephrine

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Phenylephrine

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Data

InChI: InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3

Synonyms: DivK1c_000597, Ah-Chew,1228015-39-1, Phenoptic, (R)-3-Hydroxy-alpha-((methylamino)methyl)benzenemethanol,component of Ru-tuss liquid (Salt/Mix),Neo-Synephrine Pediatric Nasal Drops,component of Dristan nasal mist (Salt/Mix), Mezaton,(R)-(-)-phenylephrine,Nostril Spray Pump Mild,Mesatonum,NCGC00024257-05,m-Sympathol, Mesatonum, Benzenemethanol, 3-hydroxy-alpha-((methylamino)methyl)-, (R)-(9CI),Benzenemethanol, 3-hydroxy-.alpha.-[(methylamino)methyl]-, (R)-,Minims Phenylephrine,Metasynephrine,I-Phrine, Ak-dilate, Mydfrin (TN),PHENYLEPHRINE [INN], Mesatone, Relief Eye Drops for Red Eyes, Isopto Frin,AM100999,Ocugestrin,Mydfrin,(alphar)-3-hydroxy-alpha-[(methylamino)methyl]benzenemethanol, M-Sympathol,Cyclomydril,Mesaton,Ak-dilate (Salt/Mix),component of Pv tussin syrup (Salt/Mix),component of Dristan cold (Salt/Mix),l-1-(m-Hydroxyphenyl)-2-methylaminoethanol,PHENYLEPHRINE [VANDF],3-[(1R)-1-hydroxy-2-methylaminoethyl]phenol,Ak-nefrin,Sudafed,Adrianol (Salt/Mix),Lopac0_000920,NCGC00024257-06,Ocu-Phrin Sterile Ophthalmic Solution,Spectrum4_000967,phenylephrine,component of Cyclomydril (Salt/Mix), Fenilefrina [INN-Spanish],59-42-7,UNII-1WS297W6MV,SBI-0050895.P004,NCGC00024257-07, Mydfrin,component of Zincfrin (Salt/Mix), Alconefrin Nasal Drops 25,Ak-dilate,Visadron,Neophryn (Salt/Mix), (-)-m-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol,Spectrum2_001280,component of Entex (Salt/Mix), Tannins, compds. with (R)-3-hydroxy-alpha-((methylamino)methyl)benzenemethanol,l-alpha-Hydroxy-beta-methylamino-3-hydroxy-L-ethylbenzene,l-.alpha.-Hydroxy-.beta.-methylamino-3-hydroxy-l-ethylbenzene, Metasynephrine,EN300-160202, Visadron,Isopto Frin,Spectrum3_000770,Alconefrin Nasal Drops 25, Phenylephrinum, Neo-Synephrine Nasal Spray,Spectrum_001101,Neo-Synephrine Nasal Spray,(-)-phenylephrine, L-1-(m-Hydroxyphenyl)-2-methylaminoethanol,Prefrin (Salt/Mix),SPBio_001280,KBio2_001581,Ocu-Phrin Sterile Eye Drops,component of Relief (Salt/Mix),(-)-m-Hydroxy-.alpha.-(methylaminomethyl)benzyl alcohol, L-(3-Hydroxyphenyl)-N-methylethanolamine,component of Hycomine compound (Salt/Mix),3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol,MFCD00044749,Metaoxedrine,Fenilefrina,Q-201560,Hemorid,(-)-3 HYDROXY-.ALPHA.-((METHYLAMINO)METHYL)BENZENEMETHANOL, M-Oxedrine,KBioGR_001313, Metasympatol, Doktors, Ocugestrin,phenylene,1416-03-1,D08365,AT-057/40243664, L-Phenylephrine,(-)-1-(3-HYDROXYPHENYL)-2-METHYLAMINOETHANOL,Phenylephrine, l-,Doktors, Metaoxedrine,Lopac-P-6126,CHEMBL1215,KBio2_004149,NCGC00015825-01,Z1198723489,DTXSID9023465,PHENYLEPHRINE [MI],β-HO-N-Me-3-HPEA,Nostril (Salt/Mix),m-Oxedrine,(R)-3-(1-hydroxy-2-(methylamino)ethyl)phenol,SDCCGSBI-0050895.P005, Duration,Rhinall,Phenylephrine Minims,Isophrin,component of Comhist (Salt/Mix),component of Decongestant (Salt/Mix),Q421910, Prefrin Liquifilm, Phenylephrine [INN:BAN], Alconefrin Nasal Spray 25,Neo-Synephrine Nasal Drops,HY-B0769, Neo-Synephrine Nasal Drops,Duo-Medihaler,component of Vasosulf (Salt/Mix), Metaoxedrinum,Mesatone,component of Prefrin-a (Salt/Mix), M-Sympatol,AS-13635,KBioSS_001581, 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol,L-PhenylephrinePhenylephrine,m-Methylaminoethanolphenol,Prefrin Liquifilm,IDI1_000597, Alconefrin Nasal Drops 50,(R)-phenylephrine,Fenilefrina [INN-Spanish], Mesaton,AB00053522_11,(-)-m-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol,3-[(1R)-1-Hydroxy-2-(methylamino)ethyl]phenol, AldrichCPR,Phenoptic,CS-6187,Neosynephrine,l-m-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol,Alcon Efrin, Phenylephrinum [INN-Latin], Metsatonum,component of Histalet forte (Salt/Mix),Alcon efrin (Salt/Mix),(-)- m-Hydroxy-a-[(methylamino)methyl]benzyl alcohol hydrochloride,1WS297W6MV,Adrianol,(-)-m-Oxedrine,Benzenemethanol, 3-hydroxy-alpha-((methylamino)methyl)-, (R)-, M-Synephrine,AKOS006282042,PHENYLEPHRINE [WHO-DD], Ocu-Phrin Sterile Eye Drops,Neophryn,Neofrin,3-[1-Hydroxy-2-(methylamino)ethyl]phenol, (R)-,AB00053522_12,CHEBI:8093, L-alpha-Hydroxy-beta-methylamino-3-hydroxy-L-ethylbenzene,component of Cerose dm (Salt/Mix),NINDS_000597, Fenilefrina,C07441,044P749,Mezaton,KBio1_000597,Phenylephrine, (r)-,BSPBio_002420,(R)-3-Hydroxy-.alpha.-[(methylamino)methyl]benzenemethanol, Metaoxedrin,3-(1-hydroxy-2-(methylamino)ethyl)phenol,component of Ru-tuss tablets (Salt/Mix),R-PHENYLEPHRINE, Phenylephrine (INN),(R)-2-Hydroxy-2-(3-hydroxyphenyl)-N-methylethylamine,Meta-synephrine,Alconefrin Nasal Drops 12,L-Phenylephrine, M-Methylaminoethanolphenol, Phenylephrine Minims,l-(3-Hydroxyphenyl)-N-methylethanolamine,EINECS 200-424-8,AB-101 (PHENYLEPHRINE),Phenylephrine HCI,KBio3_001640,component of Demazin (Salt/Mix),Dilatair, Spersaphrine,Benzyl alcohol, m-hydroxy-alpha-((methylamino)methyl)-, (-)-,l-m-Hydroxy-.alpha.-((methylamino)methyl)benzyl alcohol,m-Synephrine,AI3-02402,R(-)-Phenylephrine,A832309,m-Sympatol,Mydfrin (Salt/Mix), Alcon Efrin,CCRIS 8464, Ak-nefrin, Isophrin,ZINC113355,Metaoxedrinum,Metaoxedrin, Neofrin,J8.601K,Phenylephrinum,Neo-Synephrine,KBio2_006717, Neo-Synephrine Nasal Jelly,DB00388, Nostril Spray Pump Mild,Phenylephrine (INN),NCGC00015825-02,Relief Eye Drops for Red Eyes,Benzenemethanol, 3-hydroxy-a-[(methylamino)methyl]-, (.alpha.R)-,PHENYLEPHRINE [MART.],Alconefrin Nasal Drops 50,Phenylephrine,Duration,Alconefrin Nasal Spray 25,Ah-Chew, Neo-Synephrine,Spectrum5_001411,SCHEMBL4711,NCGC00024257-19,Phenylephrine Minims (TN),BDBM50067212,PHENYLEPHRINE [EP IMPURITY],GTPL485,3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol;L-Phenylephrine,Metasympatol,Phenylephrinum [INN-Latin],CCG-205002,R-(-)-Phenylephrine, L-m-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol, Phenylephrine Minims (TN), Minims Phenylephrine,(R)-(-)-Phenylephrine; L-Phenylephrine, R(-)-Phenylephrine, I-Phrine,PDSP1_001108,NCGC00024257-03,Prefrin, Nostril,PHENYLEPHRINE [EP MONOGRAPH], Alconefrin Nasal Drops 12, Dilatair,P0395,Spersaphrine, (R)-2-Hydroxy-2-(3-hydroxyphenyl)-N-methylethylamine, Nostril Spray Pump, Dionephrine,Ak-nefrin (Salt/Mix),BIDD:GT0157,Neo-Synephrine Nasal Jelly, Isophrim,Benzyl alcohol, m-hydroxy-.alpha.-((methylamino)methyl)-, (-)-,Nostril Spray Pump,R(-)-Mezaton,PDSP2_001092,EC 200-424-8, L-Phenylephedrine,PHENYLEPHRINE [HSDB],Dionephrine,Isophrim,Biomydrin (Salt/Mix),Phenylephrine [INN:BAN], Neosynephrine,HSDB 3383

Estimated data

Solubility: -0.453 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: Yes (prediction using frontiersin.org)

Addictivity Prediction: 35.5% (prediction based on www.mdpi.com)

Similarities

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.