WHC is still in active development. Read this to understand our approach.
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tripsit

bupropion

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isomerdesign

Bupropion

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pubchem

Bupropion

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drugmap

Bupropion

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Bupropion

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Data

InChI: InChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3

Synonyms: Bupropion-[d9],Spectrum3_000644,(+-)-2-(tert-Butylamino)-3'-chlorpropiophenon,BUPROPION [MART.], 34841-39-9,D07591,alpha-(tert-butylamino)-m-chloropropiophenone, (-)-2-(tert-Butylamino)-3'-chloropropiophenone,zyban,STL373006, 1-Propanone,AB00053756_20, alpha-(tert-butylamino)-m-chloropropiophenone,Spectrum4_000614,BDBM50048392, (-)-2-(tert-Butylamino)-3'-chlorpropiophenon, Amfebutamonum,AB00053756-19,1-PROPANONE, 1-(3-CHLOROPHENYL)-2-((1,1-DIMETHYLETHYL)AMINO)-(+/-)-,Bupropion extended release,Zyban,Propiophenone, 2-(tert-butylamino)-3'-chloro-,1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone, 34911-55-2,UNII-01ZG3TPX31,amfebutamonum,BRD-A05186015-003-05-7,AM807634,BCP24193,Bupropion (USAN),Zyban (Salt/Mix),BUPROPION [VANDF],BSPBio_000038,1-Propanone, 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-,34911-55-2,bupropion,DTXSID7022706,BRN 2101062,HSDB 6988,BUPROPION [WHO-DD],BRD-A05186015-003-09-9,AMY32517,.alpha.-(tert-Butylamino)-m-chloropropiophenone,Q834280,DivK1c_007050,Elontril,Bupropion [INN:BAN],Amfebutamonum [INN-Latin], 1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]propan-1-one,(R,S)-2-(tert-Butylamino)-3'-chloro-propiophenone,DB01156,SPBio_001817,SDCCGSBI-0050154.P004,DB-048697,KBio2_007279,(.+/-.)-Bupropion,KBio3_001467,Wellbutrin,MRF-0000143,AB00053756-18,Spectrum5_001406,NCGC00089751-02,Prestwick1_000249,1-Propanone, 1-(3-chlorophenyl)-2-[(1, 1-dimethylethyl)amino]-, Amfebutamon, Bupropion (USAN),Spectrum2_001659,Wellbatrin,SPBio_002257,1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]propan-1-one, Zyban,NCGC00015122-09, Amfebutamona,EN300-1707781, Bupropion SR,01ZG3TPX31,Bupropion slow release,AC-197,Bupropion SR, AMFEBUTAMONE HCl,NCGC00015122-14, Amfebutamona [INN-Spanish],BUPROPION [MI],NSC315851, Elont,C06860,BBL029065,BSPBio_002247, SNPPWIUOZRMYNY-UHFFFAOYSA-N,2-(tert-Butylamino)-1-(3-chlorophenyl)-1-propanone #, Alpha-(tert-butylamino)-m-chloropropiophenone,(+/-)-2-(tert-butylamino)-3'-chloropropiophenone,1-Propanone, 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-, (.+/-.)-,SCHEMBL38777,NCI60_002714,HMS2089G14,Spectrum_001663, CHEBI:3219,Wellbutrin (Salt/Mix),Bupropion (INN), Bupropion (INN),Anfebutamona, Amfebutamon,CHEMBL894, 2-(Tert-Butylamino)-3'-chloropropiophenone,CHEBI:3219,Budeprion (Salt/Mix), (+-)-1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone,KBioSS_002143,2-(Tert-Butylamino)-3'-chloropropiophenone,Amfebutamona [INN-Spanish],2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one,Prestwick2_000249, Bupropion [INN:BAN],HMS2051G10,NCGC00015122-03,BUPROPION [INN],AB00053756-16,(+-)-Bupropion,(+-)-2-(tert-Butylamino)-3'-chloropropiophenone,HMS3369P11,Amfebutamon,SpecPlus_000954,NCGC00015122-20, (+-)-Bupropion,amfebutamone,34841-39-9, Bupropion Hcl,HMS3393G10,BUPROPION COMPONENT OF CONTRAVE, Wellbatrin, Bupropion hydrocloride,NC00108,NCGC00015122-06,GTPL7135,KBio2_004711,wellbutrin,SBI-0050154.P003, 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one,AB00053756_21,KBio2_002143,NSC 758686, Bupropion (Old RN), Amfebutamone, BRN 2101062,SMR000472526, CHEMBL894, amfebutamonum, Alpha-(tert-Butylamino)-m-chloropropiophenone,Prestwick3_000249,NSC-758686,1-Propanone, 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-, (+-)-,AB00053756,3'-Chloro-alpha-(tert-butylamino)propiophenone,BPBio1_000042,Bupropion,NCGC00015122-07,(.+/-.)-2-(tert-Butylamino)-3'-chloropropiophenone,NCGC00015122-04,Lopac0_000166,MLS001424015,2-tert-Butylamino-1-(3-chlorophenyl)propan-1-one,L000725, Elontril,CCG-100858,AMFEBUTAMONE HCl,KBioGR_001168,KBio1_001994,Amfebutamona,Amfebutamone,1-Propanone, 1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-,bupropion (amfebutamone), Amfebutamonum [INN-Latin],(+-)-1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone,Prestwick0_000249,CCG-204261,AKOS015961770,HMS2232P04

Estimated data

Solubility: -2.867 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: Yes (prediction using frontiersin.org)

Addictivity Prediction: 55.0% (prediction based on www.mdpi.com)

Similarities

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.