WHC is still in active development. Read this to understand our approach.
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Orphenadrine

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Orphenadrine

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pubchem

Orphenadrine

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Orphenadrine

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Orphenadrine

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Data

InChI: InChI=1S/C18H23NO/c1-15-9-7-8-12-17(15)18(20-14-13-19(2)3)16-10-5-4-6-11-16/h4-12,18H,13-14H2,1-3H3

Synonyms: NCGC00089814-05,NCGC00089814-02,Mefenamine,Biorphen,A899996,N,N-Dimethyl-2-(2-methylbenzylhydroxy)ethylamine,ORPHENADRINE [VANDF], Mefenamine,Orphenadine,KBioSS_001525,o-Monomethyldiphenhydramine,Orphenadinum, Mialgin (TN),NCGC00015771-22, Orfro, Orphenate,KBio1_000853,Orphenate,Orphenadrinum,NCGC00015771-06, N,N-Dimethyl-2-(alpha-2-tolylbenzoyloxy)ethylamin, Banflex (TN),BSPBio_000317, Brocadisipal, Orphenadine,NCGC00015771-07,beta-Dimethylaminoethyl-2-methylbenzhydryl ether,Norgesic, 2-Methyldiphenhydramine,BSPBio_002141,KBio2_001525,CHEMBL900,N,N-Dimethyl-2-[(2-methylphenyl)(phenyl)methoxy]ethanamine #, Mephenamine,Ethanamine, N,N-dimethyl-2-[(2-methylphenyl)phenylmethoxy]-,NCGC00015771-03,DB01173,BDBM50062614,Mialgin (TN), Orphenadrine [INN:BAN],N,N-dimethyl-2-(alpha-2-tolylbenzoyloxy)ethylamine,Orfenadrina [INN-Spanish], Orphenadinum, N,N-Dimethyl-2-[(o-methyl-alpha-phenylbenzyl)oxy]ethylamine, O-Methyldiphenhydramine, Orphenadrinum,beta-Dimethylaminoethyl 2-methylbenzhydryl ether,Orfenadrina,Oprea1_476547,AB00053510_20, Phenyl-o-tolylmethyl dimethyaminoethyl ether,Ethylamine, N,N-dimethyl-2-((o-methyl-alpha-phenylbenzyl)oxy)-, N,N-dimethyl-2-{[(2-methylphenyl)(phenyl)methyl]oxy}ethanamine,Spectrum5_001036,SPBio_001255,ORP,SPBio_002238,SCHEMBL28727, Brocasipal (TN),Orphenedrine,UNII-AL805O9OG9,N,N-Dimethyl-2-[(o-methyl-alpha-phenylbenzyl)oxy]ethylamine,Lopac0_000884,NCGC00015771-12,AL805O9OG9, Biorphen, Myotrol,SBI-0050859.P004,DivK1c_000853,dimethyl-2[alpha-(o-tolyl)benzyloxy]ethylamine, Disipal (TN),KBio3_001641, Beta-Dimethylaminoethyl-2-methylbenzhydryl ether, Orfenadrina [INN-Spanish], Beta-Dimethylaminoethyl 2-methylbenzhydryl ether,N,N-dimethyl-2-(phenyl(o-tolyl)methoxy)ethanamine,Phenyl-o-tolylmethyl dimethylaminoethyl ether,Spectrum2_001038, Norflex (TN), Brocasipal,dimethyl({2-[(2-methylphenyl)(phenyl)methoxy]ethyl})amine,o-Methyldiphenhydramine,AB00053510_21, Orphenadrine(INN),Spectrum3_000531,ORPHENADRINE [WHO-DD],N,N-Dimethyl-2-[(2-methylphenyl)(phenyl)methoxy]ethanamine,Spectrum4_000460, Myolin,WS 2434,Orphenadrine, N,N-Dimethyl-2-(o-methyl-alpha-phenylbenzyl)oxy)ethylamine,NCGC00015771-10, Disipal,ORPHENADRINE [HSDB],Disipal,Prestwick2_000239, Flexon (TN), Norflex Orphenadrine Citrate,ETHANAMINE, N,N-DIMETHYL-2-((2-METHYLPHENYL)PHENYLMETHOXY)-, (+/-)-,C07935,Ethanamine, N,N-dimethyl-2-((2-methylphenyl)phenylmethoxy)-,Invagesic,Spectrum_001045,ORPHENADRINE [INN], Lysantin,Phenyl-o-tolylmethyl dimethyaminoethyl ether,CBDivE_006102, Orphenedrine, Mephenamin (TN),NCGC00089814-03,L001253,orphenadrine,NINDS_000853, 2-(Phenyl-o-tolylmethoxy)ethyldimethylamine,N,N-dimethyl-2-{[(2-methylphenyl)(phenyl)methyl]oxy}ethanamine,GTPL7251,Orphenadrin, Orfenadrina,Brocasipal (Salt/Mix),Orphenadrine (INN),N,N-dimethyl-2-[(2-methylphenyl)-phenylmethoxy]ethanamine,.beta.-Dimethylaminoethyl 2-methylbenzhydryl ether, Methyldiphenylhydramine,IDI1_000853,NCGC00015771-05, Orphenadrin,BPBio1_000349, ORP,BS-5930,EN300-708773, Sodium Mefenamine, Orphenadrinum [INN-Latin],Antiflex, N,N-dimethyl-2-(alpha-2-tolylbenzoyloxy)ethylamine,BRD-A53576514-003-03-1, N,N-Dimethyl-2-[(2-methylphenyl)(phenyl)methoxy]ethanamine,DTXSID3023396, Biorphen (TN),BRN 1885151,KBio2_004093,Orphengesic,Orfenadin,D08305, WS 2434,Q3292273,2-(Phenyl-o-tolylmethoxy)ethyldimethylamine,Orphenadrinum [INN-Latin],Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine,ORPHENADRINE [MI],SDCCGSBI-0050859.P005,AB00053510,BRD-A53576514-048-06-9,N,N-Dimethyl-2-(alpha-2-tolylbenzoyloxy)ethylamin,Orphenadrine [INN:BAN], O-Monomethyldiphenhydramine,(+/-)-N,N-DIMETHYL-2-((O-METHYL-.ALPHA.-PHENYLBENZYL)OXY)ETHYLAMINE,Prestwick3_000239,NCGC00015771-09,Brocadisipal,CCG-204966,HSDB 3139, N,N-dimethyl-2-[(2-methylphenyl)-phenylmethoxy]ethanamine,83-98-7,EINECS 201-509-2,CHEBI:7789,N,N-Dimethyl-2-[(o-methyl-.alpha.-phenylbenzyl)oxy]ethylamine,MEFENAMINE [JAN],KBioGR_000880,2-Methyldiphenhydramine,Mephenamine (Salt/Mix),4-06-00-04727 (Beilstein Handbook Reference),Ethylamine, N,N-dimethyl-2-((o-methyl-.alpha.-phenylbenzyl)oxy)-,Prestwick1_000239,AB00053510-19,N,N-Dimethyl-2-(o-methyl-alpha-phenylbenzyl)oxy)ethylamine,KBio2_006661,Prestwick0_000239

Estimated data

Solubility: -2.937 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: Yes (prediction using frontiersin.org)

Addictivity Prediction: 50.7% (prediction based on www.mdpi.com)

Similarities

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.