WHC is still in active development. Read this to understand our approach.
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isomerdesign

Lofentanil

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pubchem

Lofentanyl

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drugmap

LOFENTANIL

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wiki

Lofentanil

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Data

InChI: InChI=1S/C25H32N2O3/c1-4-23(28)27(22-13-9-6-10-14-22)25(24(29)30-3)16-18-26(19-20(25)2)17-15-21-11-7-5-8-12-21/h5-14,20H,4,15-19H2,1-3H3

Synonyms: CHEBI:61095,Lofentanila, methyl (3S,4R)-3-methyl-1-phenethyl-4-(N-propanoylanilino)piperidine-4-carboxylate,methyl 3-methyl-1-phenethyl-4-(N-phenylpropionamido)piperidine-4-carboxylate,4-Piperidinecarboxylic acid, 3-methyl-4-((1-oxopropyl)phenylamino)-1-(2-phenylethyl)-, methyl ester, cis-(-)-,Lofentanil,Lofentanil [Non stereospecific],methyl 3-methyl-1-(2-phenylethyl)-4-(N-propanoylanilino)piperidine-4-carboxylate, R 34,995,4-Piperidinecarboxylic acid, 3-methyl-4-((1-oxopropyl)phenylamino)-1-(2-phenyleethyl)-, methyl ester, (3R,4S)-rel-(-)-,methyl 3-methyl-1-(2-phenylethyl)-4-[phenyl(propionyl)amino]piperidine-4-carboxylate, D04764, UNII-6C1599T3OQ component CBKLICUQYUTWQL-XWGBWKJCSA-N,60645-00-3,DTXSID10866851,Lofentanil oxalate,R-32792, AC1L23D4,HSDB 8378, FT-0670830, R 34995,lofentanyl,Epitope ID:153512,Methyl 3-methyl-1-(2-phenylethyl)-4-(phenyl(propionyl)amino)-4-piperidinecarboxylate,CHEMBL3990749, cis-(-)-4-(Methoxycarbonyl)-3-methyl-1-phenethyl-4-(N-phenylpropionylamino)piperidinium hydrogen oxalate, Lofentanil oxalate [USAN],SCHEMBL1952939, (-)-Methyl cis-3-methyl-1-phenethyl-4-(N-phenylpropionamido)isonipecotate oxalate (1:1),Methyl cis-(-)-3-methyl-4-((1-oxopropyl)phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylate, Lofentaniloxalat,Lofentanilum,Q27130652, 61380-41-4, EINECS 262-750-7,R 32792, Lofentanil oxalate (USAN),4-Piperidinecarboxylic acid, 3-methyl-4-((1-oxopropyl)phenylamino)-1-(2-phenylethyl)-, methyl ester

Estimated data

Solubility: -4.355 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: Yes (prediction using frontiersin.org)

Addictivity Prediction: 80.4% (prediction based on www.mdpi.com)

Similarities

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.