WHC is still in active development. Read this to understand our approach.
depiction of DIWRORZWFLOCLC-UHFFFAOYSA-N.svg
tripsit

lorazepam

Check on tripsit

psychonaut

Lorazepam

Check on psychonaut

isomerdesign

Lorazepam

Check on isomerdesign

druglab

Lorazépam

Check on druglab

drugmap

Lorazepam

Check on drugmap

wiki

Lorazepam

Check on wiki

Data

InChI: InChI=1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)

Synonyms: HMS2052H07,Nervistopl,IDI1_000965, Novartis Brand of Lorazepam, Lorazepam Wyeth Brand, Donix, Bonatranquan,LORAZEPAM [WHO-DD], Duralozam,SCHEMBL26961,o-Chloroxazepam,Quait,DSSTox_RID_76932,Lorsilan,Emotion, Wyeth Brand of Lorazepam,7-Chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one,Lorazepam preservative free, Lorazepam-Efeka,Lorazepam, United States Pharmacopeia (USP) Reference Standard, Medix Brand of Lorazepam,DB00186,Lopam,Lorazepam Medical,HMS503A11, Medical Brand of Lorazepam,Stapam, Lorazep, Novopharm Brand of Lorazepam,Apo-Lorazepam, Lorivan,7-chloro-3-hydroxy-5-(2'-chloro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepine-2-one, Renaquil,LORAZEPAM [ORANGE BOOK], Bonton, (+/-)-Lorazepam,Securit, Lorazepam Medical Brand,Ativan (TN), Tolid,7-chloro-3-hydroxy-5-(2'-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepine-2-one,NINDS_000965, Medical, Lorazepam, O-Chlorooxazepam,Tavor,Lorazepam, European Pharmacopoeia (EP) Reference Standard,LORAZEPAM [INN], Lorazepam Llorens Brand, Aplacasse,EINECS 212-687-6,Lorsedal, Lorazon, Nervistop L, Securit, Lorazepam (Ativan), Tranqipam,Pro dorm, Ativan,LORAZEPAM7-Chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one,Lorazepam, British Pharmacopoeia (BP) Reference Standard, Wyeth, Orfidal,NC00420,Lorat, Baxter Brand of Lorazepam,846L491,Wy 4036, Lorazepam (JP15/USP/INN), Sedizepan,Lorazin,O26FZP769L,Sedizepan,Novhepar, Larpose,Lorazon,Idalprem, Lorazepamum, Alzapam, Lorazepam-ratiopharm, Ativan (TN), Lorazepam Riemser Brand, Equitam,Lorazepam 0.1 mg/ml in Acetonitrile,Norlormetazepam, Lorazepam Dolorgiet Brand, Lorazepam preservative free, Novo-Lorazem,Lorax, Vigiten,Merlit,7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-1,4-benzodiazepin-2(3H)-one, Lorazep von ct, 7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one,Wypax, 7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one,LOREEV XR,LORAZEPAM [MI], Apo Lorazepam,BCP13713,LORAZEPAM [EP IMPURITY],Sinestron,Lorazene, Idalprem, Pro dorm,CCG-101170, Temesta, WY4036,KBio1_000965, Emotion,Q408265, Lorenin,Vigiten,7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one,DSSTox_GSID_23225,DivK1c_000965, Lorazepam Medix Brand, Ct-Arzneimittel Brand of Lorazepam,Tox21_111669,NSC 289758,MLS001424236,BRN 0759084, Dolorgiet Brand of Lorazepam,Lorazepam 1.0 mg/ml in Acetonitrile, L1764_SIGMA,UNII-O26FZP769L, 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one, Loridem, Lorazepam Desitin Brand, Lorazepam ratiopharm,2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-, Riemser Brand of Lorazepam,(RS)-9-chloro-6-(2-chlorophenyl)-4-hydroxy-2,5-diazabicyclo[5.4.0]undeca-5,8,10,12-tetraen-3-one, Lorazepam Genericon, Novhepar,Loraz,(+/-)-7-CHLORO-5-(O-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-2H-1,4-BENZODIAZEPIN-2-ONE,Lorans,Anxiedin,Sidenar, Lorazepam Novartis Brand,Temesta, Lorazepam neuraxpharm Brand,Orfidal,2H-1, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-, Merlit,7-chloro-5-(2-chlorophenyl)-3-hydroxy-2,3-dihydro-1H-1,4-benzodiazepin-2-one,Lomesta,Silence, Lorazepamum [INN-Latin], Durazolam,Renaquil,LORAZEPAM [VANDF],Almazine,Sedatival,Lorazepamum [INN-Latin], Azurogen,Bonton, Ratiopharm Brand of Lorazepam, Norlormetazepam, Lorabenz,DEA No. 2885, Anxiedin,Nervistop L, Lomesta,Demethyllormetazepam,Lorazepan Chobet, Wy 4036, Nu-Pharm Brand of Lorazepam,Efasedan, Trapax, Nervistopl, Wy-4036, O-Chloroxazepam,Lorenin,7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one, Lozepam, Lorafen,7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one #,o-Chlorooxazepam,LORAZEPAM [MART.], Lorazepam Novopharm Brand, Sedatival,Upan,Max Pax,7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one,Larpose, Novolorazem,846-49-1,Lorazepam civ, Silence, Lorazepam Lannacher, Loraz, Ct Arzneimittel Brand of Lorazepam, Lorzem,2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-, (+-)-, Anxira,CAS-846-49-1,Laubeel,BDBM50292627,Lozepam, Lorazepam Fabra,Delormetazepam, Temesta (TN),DTXCID303225,NSC-289758,L-230, Somagerol,Lorapam, Lorazepam Medical, Nu Pharm Brand of Lorazepam,Lorazepam solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material,Aripax, Lorazepam Nu-Pharm Brand,Azurogen,BRD-A11990600-001-01-8,(+-)-7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one,Lorzem, Llorens Brand of Lorazepam,Lorafen,DTXSID7023225, Lorazepam neuraxpharm,Lorazepan Richet, Aripax,O-Chloroxazepam; O-Chlorooxazepam; Almazine; WY 4036; WY-4036; WY4036, Lorsedal,Lorazepamum,WLN: T67 GMV JN IHJ CG IQ KR BG, Lorapam,Lorazepam Fabra, Lopam, Lorazene,Lorazepam [USAN:USP:INN:BAN:JAN],Lorazepam Lannacher,NSC289758,D00365,Lorazepam Genericon,LORAZEPAM [JAN], Quait, Sinestron,(.+/-.)-Lorazepam, Sedicepan, Orfidal Wyeth, Novo Lorazem, Lorat,Lorazepam (JP17/USP/INN), Laubeel, Sedazin, Lorazepam ct-Arzneimittel Brand,Tranqipam, Wypax, Apo-Lorazepam,Kalmalin,2H-1, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-, Lorazepam AHP Brand,LORAZEPAM [USAN], Lorazepam [USAN:INN:BAN:JAN], Rocosgen, Lorazin, Lorazepan Richet,Donix, Lorazepam Baxter Brand,GTPL5884,SMR000058410,Bonatranquan, Upan,Tolid,HMS3394H07,7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one, Punktyl, Delormetazepam,Equitam, ApoLorazepam,lorazepam,Anxira,A840886,Lorivan, Lorans,Lorazepam-Efeka,ativan,5-25-02-00248 (Beilstein Handbook Reference), Anzepam,Duralozam, (+-)-7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one,LORAZEPAM [EP MONOGRAPH], Neuraxpharm Brand of Lorazepam,CHEBI:6539,Somagerol, Stapam,2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-5-(2-CHLOROPHENYL)-1,3-DIHYDRO-3-HYDROXY-, (+/-)-,7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one.,Wy-4036, NuLoraz, 7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-1,4-benzodiazepin-2(3H)-one,Emotival, Aplacassee, Sidenar, Lorsilan, Desitin Brand of Lorazepam,(+/-)-Lorazepam, Lorazepan Chobet, Loram,7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-benzo[e][1,4]diazepin-2(3H)-one,LORAZEPAM [USP MONOGRAPH], AHP Brand of Lorazepam,Punktyl,2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-,Loram, Lorazepam ratiopharm Brand,Lorabenz,7-chloranyl-5-(2-chlorophenyl)-3-oxidanyl-1,3-dihydro-1,4-benzodiazepin-2-one, Nu Loraz, Lorax,Lorazepam,7-Chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one (lorazepam),7-Chloro-5-(o-chlorophenyl)-1,4-benzodiazepin-2-one, Emotival,Anzepam,Nu Loraz,LORAZEPAM CIV [USP-RS], Orfidal,Rocosgen, Max Pax,Lorazepam Intensol, Lorazepam-neuraxpharm, Lorazepam Intensol, Tavor,7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepine-2-one,Trapax,Ativan, 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one,CHEMBL580,Aplacassee, Lorazepam Apotex Brand, Serra Pamies Brand of Lorazepam, Merck dura Brand of Lorazepam, Efasedan, Nu-Loraz,Sedazin,Lorazep, Apotex Brand of Lorazepam,Loridem,Aplacasse,Novolorazem, Kalmalin,AKOS015904303,DSSTox_CID_3225, Demethyllormetazepam,NCGC00159439-02,Lorazepam for system suitability, European Pharmacopoeia (EP) Reference Standard

Estimated data

Solubility: -4.218 (log(S) in mol/L prediction using SolTranNet)

Blood Brain Barrier Permeability: No (prediction using frontiersin.org)

Addictivity Prediction: 51.8% (prediction based on www.mdpi.com)

Similarities

The following is a set of comparisons to understand the properties of this compound. This is still higly experimental and is still under active development. Please refer to our series of blog posts to fully understand our approach and its limitations. This information is for informational purposes only and should not be construed as medical advice.