Noscapine
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Noscapine
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Noscapine
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Data
InChI: InChI=1S/C22H23NO7/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18/h5-6,9,17-18H,7-8,10H2,1-4H3
Synonyms: (+/-)-Noscapine,5-(6,7-Dimethoxyphthalidyl)-5,6,7,8-tetrahydro-4-methoxy-8-methyl-1,3-dioxolo(4,5-g)isoquinoline,Tusscapine,NCGC00023230-14,AC-20272,NCGC00016388-01,VS-03291,DTXSID4023385,(-)-alpha-narcotine,NSC-121869,NSC-5366,Methoxyhydrastine,NOSCAPINE [HSDB],NARCOTINUM [HPUS],NSC 96350,Noscapina [INN-Spanish],8V32U4AOQU,Key-tusscapine,DTXSID901032089,Vadebex,NCGC00023230-04,.beta.-Narcotine,O-Methylnarcotoline,BRD-K89237706-001-03-8,Terbenol,(-)-a-Narcotine,Phthalide, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-,NSC121869,Narcotussin,CS-5115,1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R*,S*)-,Noscapine (JP17/USP/INN),1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (S-(R*,S*))-,NOSCAPINE [WHO-DD],(-)-3-(2-Methyl-6,7-methylendioxy-8-methoxy-1-isochinolyl)-6,7-dimethoxyphthalid,dl-Narcotine,Longactin,Narcotine alkaloid,(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone,SCHEMBL4559,(3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-1,3-dihydro-2-benzofuran-1-one,Narcosine,C09592,Coscopin (VAN),SR-01000075529-6,NCGC00023230-08,Tox21_110413_1,NOSCAPINE [INN],DSSTox_GSID_23385,W-201012,L-alpha-2-Methyl-8-methoxy-6,7-methylenedioxy-1-(6,7-dimethoxy-3-phthalidyl)-1,2,3,4-tetrahydroisoquinaline,AKOS000278036,D01036,Prestwick3_000563,HSDB 3372,GTPL10212,6,7-Dimethoxy-3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-2-benzofuran-1(3H)-one, (S-(R*,S*))- #,Noscapine (JP15/USP/INN),NCGC00023230-05,Opian,Prestwick0_000563,WLN: T C566 DO FO KN EH & & TJ HO1 K1 J-DT56 BVO DHJ HO1 IO1,Noscapine [USP:INN:BAN:JAN],NOSCAPINE, (+/-)-,UNII-A4C6WE7BZN,Coscopin,L-alpha-Narcotine,NOSCAPINE [USP-RS],NOSCAPINUM [WHO-IP LATIN],Noscapine dl-form,L-alpha-Noscapine,SPBio_002565,NCGC00023230-07,1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-((5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (3S)-rel-,Noscapal,(-)-Narcotine,NSC 5366,Tox21_110413,Noscapinum [INN-Latin],HMS2096B08,4-27-00-06838 (Beilstein Handbook Reference),alpha-Narcotine,NOSCAPINE [MART.],NCGC00023230-10,HMS1569B08,(-)-alpha-Norcotine,Noscapinum,NOSCAPINE [EP MONOGRAPH],BIM-0048054.P001,Tocris-1697,L-.alpha.-Narcotine,Opianine,NCGC00023230-02,BBL012344,(-)-noscapine,NOSCAPINE [WHO-IP],(3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one,(+/-)-.ALPHA.-NARCOTINE,CHEBI:73237,NOSCAPINE [JAN],NCI60_004322,1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, [S-(R*,S*)]-,.alpha.-Narcotine,MLS001060855,128-62-1,Noscapina,NSC-96350,(+-)-Noscapine,CHEMBL364713,[S-(R*,S*)]-6,7-Dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-1(3H)-Isobenzofuranone,NARCOTINE,Noscopine,Prestwick2_000563,DSSTox_CID_3385,BPBio1_000382,8-Methoxyhydrastin,NOSCAPINE DL-FORM [MI],Lyobex,Coscotabs,Prestwick_959,Narcompren,BRN 0099933,Nipaxon,MFCD00069316,(3S)-6,7-Dimethoxy-3-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-2H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2-benzofuran-1(3H)-one,CAS-128-62-1,UNII-8V32U4AOQU,Gnoscopine,Prestwick1_000563,(S,R)-Noscapine, 97%,Lopac0_000840,(3S)-3-[(5R)-6-methyl-4-(methyloxy)-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6,7-bis(methyloxy)-2-benzofuran-1(3H)-one,(+-)-alpha-Narcotine,BSPBio_000346,Narkotin,Capval,Noscapalin,AC-33191,Noscapine, European Pharmacopoeia (EP) Reference Standard,Noscapine 1.0 mg/ml in Acetonitrile,Nicolane,Longatin,1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R*,S*)-(+-)-,DSSTox_RID_77007,Noscapine (TN),6035-40-1,Narcotine,Noscapine,noscapine,HMS2269P05,Nectadon,(3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2-benzofuran-1(3H)-one,CBMicro_048259,(3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one,1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)-isoquinolin-5-yl), (S-(R*,S*))-,1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-((5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (3S)-,A4C6WE7BZN,(S)-6,7-dimethoxy-3-((R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuran-1(3H)-one,Q60998699,.alpha.-Gnoscopine,1-.alpha.-Narcotine,Noscapine, United States Pharmacopeia (USP) Reference Standard,Noscapin,HY-13716,NOSCAPINE [USP MONOGRAPH],BDBM50424716,Opianin,[S-(R*,S*)]-6,7-Dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo-[4,5-g]-isoquinolin-5-yl)-1-(3H)-isobenzofuranone,Hederix (free base),Phthalide,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-,1(3H)-Isobenzofuranone,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, [S-(R*,S*)]-,(-)-.alpha.-Narcotine,Narcotinum,NSC5366,Narcotine, (+-)-,(-)-.alpha.-Norcotine,SMR000059119,Noskapin,CCRIS 9304,EINECS 204-899-2,NOSCAPINE [MI],CCG-204096,DB06174,Narcotin,ZINC19418974,STK054401,MLS000069475,alpha-Gnoscopine,SDCCGSBI-0048054.P004,EN300-24402818,08N
Estimated data
Solubility: -3.549 (log(S) in mol/L prediction using SolTranNet)
Blood Brain Barrier Permeability: Yes (prediction using frontiersin.org)
Addictivity Prediction: 38.9% (prediction based on www.mdpi.com)
