Gly

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Gly

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Glycine

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Glycine

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SMILES:NCC(=O)O

InChI:InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key:DHMQDGOQFOQNFH-UHFFFAOYSA-N

Synonyms: Glycinum, 2,2-dialkylglycines, Glycosthene, L-Glycine, Hgly, Acido aminoacetico, An alpha amino acid ester, Glycine iron sulphate (1:1),Aciport, Aminoessigsaeure, Polyglycine II, Glykokoll, Corilin, Glicoamin, Amitone, Glycine-UL-14C hydrochloride, Polyglycine, Glycin, (1-13c)glycinato, Hampshire glycine,Glycine, Glycine [INN], Sucre de gelatine, Padil,Gly, Glicina [INN-Spanish], (15N)Glycine, Aminoacetic acid, Aminoethanoic acid, L-alpha-amino acids, AB-131/40217813, Aminoazijnzuur, Glicina, Leimzucker, Glycinum [INN-Latin], GLYCINE, ACS, Acidum aminoaceticum [INN-Latin], Gly, Glycolixir, Acide aminoacetique, Glycine, labeled with carbon-14, Glycine, homopolymer (VAN), H-Gly-OH, AMINOACETIC ACID 1.5% IN PLASTIC CONTAINER, H2N-CH2-COOH, Acido aminoacetico [INN-Spanish], Acidum aminoaceticum, Gyn-hydralin, Glycocoll, Glycine, non-medical, Acide aminoacetique [INN-French], Glyzin, 2-Aminoacetic acid, Glycine (JP15/USP), GLYCINE 1.5% IN PLASTIC CONTAINER, S04-0135, GLY (IUPAC abbrev)

Similarities

Being able to identify molecules that are similar to the one we study can allow to infer some of its properties. There are several ways of measuring the similarity between molecules, by their structure, effects, pharmacological interactions etc. In the following, you can find similar molecules according to various criterions and tools that we developed. To understand the limitations of these comparisons, it is crucial to always refer to the methodology that was used to measure those similarities. Please note: This information is provided solely for informational purposes and should not be interpreted as medical advice.

To measure structural similarity, we use the Mol2vec method, which is a neural network that processes molecules and transform them into points in spaces, such that molecules with chemically related substructures are transformed into points that are close in space.

Molecule properties

Using the KGPT Deep Learning model, we predict several property of the molecule. Predictions are grouped by the dataset that was used to get those prediction. Along with each prediction, we provide a plot that shows the distribution of predicted values on the train/test/val dataset. This gives an estimate of the reliability of the model.

Description: A dataset focused on predicting the inhibitory effects of molecules on the enzyme beta-secretase 1 (BACE1). BACE1 inhibition is a potential target for Alzheimer's disease treatment.
Class
TrainValTest
2.88-3.70-1.36
Description: A dataset providing insights on the ability of molecules to penetrate the blood-brain barrier. Crucial for understanding the potential of molecules as central nervous system drugs.
p_np
TrainValTest
-2.24-3.290.40
Description: This dataset deals with the FDA approval status and clinical trial toxicity of molecules. Important for understanding the safety and regulatory status of compounds.
CT_TOX
TrainValTest
-0.49-0.78-0.91
FDA_APPROVED
TrainValTest
0.53-1.27-0.50
Description: A dataset that predicts the solubility of molecules in water. Solubility is an essential property influencing bioavailability and the potential formulation of a drug.
logSolubilitylog(mol/L)
2.38
TrainValTest
Description: This dataset is centered on predicting the free energy when a molecule is dissolved in water. The energy changes can affect molecular interactions in biological systems.
freesolvkcal/mol
-2.26
TrainValTest
Description: A dataset predicting the lipophilicity of molecules. Lipophilicity is a crucial factor affecting the distribution, metabolism, and excretion of drugs in the body.
lipoAlogP
-2.52
TrainValTest
Description: This dataset gives insights into the metabolic stability of molecules. High metabolic stability often results in a longer half-life, influencing drug dosage and frequency.
low
TrainValTest
-0.17-3.50-2.88
high
TrainValTest
0.72-3.55-0.49
27 entries
12 entries
617 entries

Advanced insights

In the following we provide more advanced analysis about the interactions of a molecule with the human metabolism, docking sites etc.

Affinities

Binding affinities with a list of 61 predefined docking sites. Those affinities are used to compute the interactions similarities.

Interaction of this molecule with metabolism

We use a Deep Learning model to predict the interactions of this molecule with metabolism. Refer to the source to understand the methodology.

Reactions that metabolize this molecule
Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Methylation 2566
Enzymes: Glycine N-methyltransferase
Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Synthesis 2625
Enzymes: Glutathione synthetase
Reagents
Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents
Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents
Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Synthesis 3056
Enzymes: 5-aminolevulinate synthase, erythroid-specific, mitochondrial
Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Acylation 2548
Enzymes: Glycine N-acyltransferase
Acylation 2549
Enzymes: Glycine N-acyltransferase
Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Ligation 4982
Enzymes: Trifunctional purine biosynthetic protein adenosine-3
Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Acylation 1020
Enzymes: Bile acid-CoA:amino acid N-acyltransferase
Amine group addition 477
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Acylation 1023
Enzymes: Bile acid-CoA:amino acid N-acyltransferase
Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Methylation 2438
Enzymes: Glycine cleavage system H protein, mitochondrial
Reagents

Metabolite: InChI=1S/CO2/c2...

Methylation 2566
Enzymes: Glycine N-methyltransferase
Reagents

Metabolite: InChI=1S/C3H7NO...

Amidine group addition 2407
Enzymes: Glycine amidinotransferase, mitochondrial
Reagents

Metabolite: InChI=1S/C3H7N3...

Acylation 3377
Enzymes: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Reagents

Metabolite: InChI=1S/C4H7NO...

Methylation 2550
Enzymes: Serine hydroxymethyltransferase, cytosolic
Reagents

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: D-amino-acid oxidase
Reagents

Metabolite: InChI=1S/C2H2O3...

Reactions that metabolism produce from this molecule
Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 3367
Enzymes: Kynurenine--oxoglutarate transaminase 3
Products
Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Keto hydrolysis BTMR0254
Enzymes: EC 3.7.1.
N-Dealkylation of acyclic secondary amine BTMR1140
N-Dealkylation of acyclic secondary amine BTMR1140
Dipeptide hydrolysis BTMR1327
Enzymes: 3.4.13.18
N-Dealkylation of acyclic secondary amine BTMR1140
Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

N-Dealkylation of acyclic secondary amine BTMR1140
Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products
Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 3367
Enzymes: Kynurenine--oxoglutarate transaminase 3
Products

Metabolite: InChI=1S/C10H12...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Keto hydrolysis BTMR0254
Enzymes: EC 3.7.1.
Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Dehydrogenation from CyProduct BTMR1338
Enzymes: Sarcosine dehydrogenase, mitochondrial
Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 3367
Enzymes: Kynurenine--oxoglutarate transaminase 3
Products

Metabolite: InChI=1S/C10H12...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

N-Dealkylation of acyclic secondary amine BTMR1140
Keto hydrolysis BTMR0254
Enzymes: EC 3.7.1.
Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Dipeptide hydrolysis BTMR1327
Enzymes: 3.4.13.18
Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C2H2O3...

Oxidation from CyProduct BTMR1330
Enzymes: Peroxisomal sarcosine oxidase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 5408
Enzymes: Serine--pyruvate aminotransferase
Products

Metabolite: InChI=1S/C3H7NO...

Amine group addition 475
Enzymes: Alanine--glyoxylate aminotransferase 2, mitochondrial
Products

Metabolite: InChI=1S/C3H7NO...